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GFP基因重组病毒在神经解剖研究中的应用 被引量:5

APPLICATION OF GFP GENE RECOMBINANT VIRUS IN THE NEUROANATOMICAL STUDIES
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摘要 绿色荧光蛋白 (GFP)基因重组病毒标记技术是神经解剖研究的新方法。此方法可以用于观察神经元的形态学特点、神经活性物质及其受体的化学构筑、神经元形态与投射终止部位和功能的关系以及有关的局部神经环路。该法弥补了以往形态学研究方法的一些缺陷 ,能为机能学研究提供直接的形态学证据。 The green fluorescence protein (GFP) gene recombinant virus labeling is a new method for the neuroanatomical studies. It is effective to investigate the morphological features of neurons, the chemical architectures (neural active substances and their receptors) of the neurons, the relationships between the neuronal morphological features and their termination areas or their functions, and local circuits related to specific functions. This method remedies the defects of previous morphological methods and could provide direct morphological evidence for the functional investigations.
作者 李云庆
出处 《解剖学报》 CAS CSCD 北大核心 2002年第3期305-311,共7页 Acta Anatomica Sinica
基金 国家自然科学基金 ( 39970 2 39 30 0 0 0 5 2 ) 国家基础重点研究规划项目 (G19990 5 40 0 4) 高等学校骨干教师资助计划资助项目
关键词 绿色荧光蛋白 基因重组病毒 神经元 形态学研究 应用 GFP Gene recombinant virus Neuron Morphological study
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