摘要
环已酮与苯甲醛和芳香胺在催化最浓盐酸或HCl-EtOH催化下能直接进行Mannich反应,用新方法——一步法合成了2-(α-芳氨基)苄基环己酮,共合成6个化合物,其中有一个是新的化合物.产率很高.对Mannich碱生成的条件进行了讨论.
In the presence of catalytic amount of concentrated hydrochloric acid or ethanolic-HCl solution, the Mannich reaction among cyclohexanone, benzaldehydc and arylamines was carried out directly to form 2-(α-arylamino) benzyl cyclohexanones. This is a new method for the direct synthesis of 2-(α-arylamino) benzyl cyclohexanones six compounds were prepared, in which there was one now compond. The yields were good. The reaction conditions were discussed.
出处
《西南师范大学学报（自然科学版）》
CAS
CSCD
1991年第2期200-204,共5页
Journal of Southwest China Normal University(Natural Science Edition)
关键词
苄基环己酮
Mahnich反应
苯甲醛
Mannich bases
Mannich reaction
benzaldehyde
arylamine
cyclohexanone.
