摘要
目的:探讨艾灸督脉对血管性轻度认知障碍(vMCI)患者神经心理学量表及磁共振波普分析NAA/Cr、CHO/Cr值的影响。方法:将vMCI患者随机分为艾灸百会、大椎、命门的灸疗组(30例)、口服盐酸多奈哌齐对照组(30例)。观察治疗前后两组患者MMSE量表、MoCA(北京版)及血管性痴呆辨证量表(SDSVD)评分及左侧海马区磁共振波普分析(MRS)NAA/Cr、CHO/Cr值的改变。结果:艾灸督脉组与口服多奈哌齐组治疗前后MMSE量表、MoCA量表积分差异有统计学意义(P<0.05),且疗效比较显示艾灸治疗组优于西药对照组;艾灸督脉组治疗后SDSVD评分显著改善(P<0.05)。灸疗组与口服多奈哌齐组MRS的NAA/Cr值、Cho/Cr值治疗前后差异分别具有统计学意义(P<0.05),升高左脑区NAA/Cr值两组差异有统计学意义。结论:艾灸督脉百会、大椎、命门可以通过改善脑部代谢促进vMCI患者认知功能恢复,疗效优于口服多奈哌齐。
Objective:To observe the influence of neuropsychological scales and NAA/Cr、CHO/Cr ratio on the curative effect of Moxibustion DU Meridian intervention therapy for vascular mild cognitive impairment.Methods:A total of seventy-two patients diagnosed with vMCI were randomly assigned to the moxibustion treatment group and the control group.The therapy group was treated by moxibustion at baih ui dazhui mingmen,and the control group was treated by donepezil.The neuropsychological scales,NAA/Cr CHO/Cr was used to evaluate the patients′ curative effect.Results:After treatment,the scores of MMSE、MoCA and the TCM-scale assessment were improved apparently(P<0.05),with better results in the observation group(P<0.05).The significant differences(P<0.05) of increase on NAA/Cr ratio were observed between the two groups after treatment.The CHO/Cr ratio were statistically lower(P<0.05) between pre-treatment and post-treatment.Conclusion:The treatment of Moxibustion on DU Meridian was markedly superior to that of Donepezil on treating patients with vascular mild cognitive impairment,The moxibustion on DU Meridian can improve brain metabolism,is effective in reducing clinical symptoms.
作者
朱才丰
杨骏
蔡圣朝
潘洪萍
贺成功
梁猛军
ZHU Caifeng;YANG Jun;CAI Shengchao;HE Chengong;PAN Hongping;LIANG Mengjun(The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine,Hefei 230061,Anhui,China;The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine,Hefei 230061,Anhui,China)
出处
《辽宁中医杂志》
CAS
2019年第1期132-135,共4页
Liaoning Journal of Traditional Chinese Medicine
基金
国家自然科学基金项目(81603701)
安徽中医药大学临床科研基金(2014lc01011)
安徽高校自然科学研究重点项目(KJ2016A416)
安徽省软件科学研究计划项目(1607a0202075)
关键词
血管性轻度认知障碍
艾灸
督脉
神经心理学量表
磁共振波谱分析
vascular mild cognitive impairment
moxibustion
DU meridian
neuropsychological scales
magnetic resonanc spectroscopy
