摘要
报道了一种钯催化、乙酸亚铜盐促进的嘧啶硫醚/喹啉硫醚与炔烃或芳基硼酸的脱硫碳碳偶联反应,合成了一系列2-炔基嘧啶和2-芳基嘧啶/喹啉衍生物,产率良好(64%～87%).所用的乙酸亚铜盐廉价、稳定,反应产率高,底物适用范围较广.
An efficient method for carbon-carbon bond formation via desulfurative coupling of pyrimidine thioethers/ 4-phenylquinoline thioethers with alkynes or arylboronic acids is described.The reaction was promoted by a cheap and stable copper salt [copper(I)acetate]and catalyzed by palladium with good yields and wild substrate scope.
作者
刘伯渠
燕中飞
权正军
Liu Boqu;Yan Zhongfei;QuanZhengdun(Department of Chemistry and Life Science,Gansu Normail University for Nationalities,Hezuo 747000;College of Chemistry and Chemical Engineering,Northwest Normal University,Lanzhou 730070)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2018年第11期3032-3038,共7页
Chinese Journal of Organic Chemistry
基金
西北师范大学科研创新基金(No.NWNU-LKQN-15-1)资助项目~~
