摘要
目的观察胸腔镜手术与传统开放手术对食道癌患者术后疼痛及免疫功能的影响。方法将2016年11月‐2017年10月该院治疗的98例食道癌患者作为研究对象,将其依照随机数表法分为两组,均49例。观察组行胸腔镜手术,对照组行传统开放手术。观察两组近期疗效、手术情况、疼痛程度、并发症及手术前、后免疫功能变化情况。结果两组治疗总有效率对比,差异无统计学意义(P>0.05);两组术中出血量、视觉模拟评分法(VAS)评分及并发症发生率对比,观察组少于对照组,差异有统计学意义(P <0.05);治疗前两组T淋巴细胞(CD3^+、CD4^+)、免疫球蛋白A(IgA)、免疫球蛋白G(IgG)水平对比,差异无统计学意义(P>0.05);治疗后观察组CD3^+、CD4^+、IgA、IgG水平高于对照组,差异有统计学意义(P <0.05)。结论将胸腔镜手术用于食道癌治疗中效果确切且创伤较小,利于减轻患者术后疼痛与对免疫功能的影响,促进患者术后康复。
【Objective】To observe the effect of thoracoscopic surgery and traditional open surgery on postoperative pain and immune function in patients with esophageal cancer.【Methods】Ninety-eight patients with esophageal cancer treated in our hospital from November 2016 to October 2017 were selected, and they were divided into two groups by random number table, with 49 cases in each group. The observation group was given thoracoscopic surgery, while the control group was given traditional open surgery. The short-term efficacy, surgical conditions, pain degree, complications, changes of immune function in the two groups were observed.【Results】There was no statistical difference in the total effective rate between the two groups(P >0.05); the intraoperative bleeding volume, Visual Analogue Scale(VAS) score, incidence of complications in the observation group were less than those in the control group(P <0.05); before treatment, there was no statistical difference in the levels of T lymphocytes(CD3^+, CD4^+), immunoglobulin A(IgA), immunoglobulin G(IgG) between the two groups(P >0.05); after treatment, the levels of CD3^+, CD4^+, IgA, IgG in the observation group were higher than those in the control group(P <0.05).【Conclusion】Thoracoscopic surgery in treatment of esophageal cancer is effective and has smaller trauma, it can reduce postoperative pain and the effect on immune function, promote patients’ postoperative recovery.
作者
闫付庆
黄雪晖
YAN Fuqing;HUANG Xuehui(Department of Thoracic Surgery,Nanyang Second People 's Hospital in Henan Province,Nanyang,Henan 473000,China)
出处
《中国医学工程》
2018年第11期22-25,共4页
China Medical Engineering
关键词
食道癌
胸腔镜手术
传统开放手术
术后疼痛
免疫功能
并发症
esophageal cancer
thoracoscopic surgery
traditional open surgery
postoperative pain
immune function
complications
