摘要
目的探讨血清中几种常见肿瘤标志物的检测在胃癌化疗效果评价中的应用情况。方法选取经手术与病理学确认的183例胃癌患者为研究对象,患者经标准化疗方案后,根据影像学诊断结果(CT)评价疗效,根据疗效将患者分组。化疗前和影像学评价时对患者的血清肿瘤标志物进行检测,并统计各组检测结果,分析变化趋势。结果评价为CR/PR的患者治疗后与治疗前相比肿瘤标志物水平下降(P<0.05),评价为SD的患者治疗后与治疗前相比肿瘤标志物变化不显著(P>0.05),评价为PD的患者治疗后与治疗前相比肿瘤标志物水平上升(P<0.05)。结论血清中肿瘤标志物检测的变化趋势可应用于胃癌标准化疗方案疗效评价。
Objective to explore the application of several common tumor markers in serum to evaluate the effect of chemotherapy in gastric cancer. Methods 183 cases of gastric cancer confirmed by surgery and pathology were selected as study objects. After the standard chemotherapy regimen, the patients were evaluated according to the imaging diagnostic results(CT), and the patients were divided according to the curative effect. The serum tumor markers of the patients were tested before chemotherapy and during imaging evaluation. The test results were analyzed and the trends were analyzed. Results the level of tumor markers decreased after treatment compared with pre-treatment in CR/PR patients(P<0.05). The tumor markers in patients with SD were not significantly changed after treatment compared with pre-treatment(P> 0.05). The level of tumor markers increased after treatment compared with pre-treatment in patients with PD(P<0.05). Conclusion the change trend of serum tumor markers can be used to evaluate the curative effect of standard chemotherapy for gastric cancer.
作者
胡志良
陈湘陶
HU Zhi-liang;CHEN Xiang-tao(Department of Gastroenterology Surgery,First People's Hospital of Kashi District,Kashi,Xinjiang,844000;Department of General Medicine,Second People's Hospital of Kashi District,Kashi,Xinjiang,844000)
出处
《智慧健康》
2018年第30期11-12,共2页
Smart Healthcare
关键词
血清
瘤标志物
胃癌
化疗
疗效评估
Serum
Tumor markers
Gastric cancer
Chemotherapy
Curative effect evaluation
