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非胰岛素依赖性糖尿病的药物治疗及进展 被引量:6

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摘要 Ⅱ型糖尿病 (非胰岛素依赖性糖尿病、NIDDM )是一种由胰岛素分泌及其功能缺陷之间互相影响所引起的异质性疾病。通常治疗Ⅱ型糖尿病的药物有磺酰脲、二甲双胍、α 糖苷酶抑制剂 (阿卡波糖 ) ,这些药物可以单用 ,也可以合用。随着对糖尿病基础理论研究的深入 ,以及临床药理学的迅速发展 ,治疗糖尿病的药物已突破了传统的磺酰脲类、双胍类等化学结构上的限制 。
作者 李后开
出处 《安徽医药》 CAS 2001年第4期244-245,共2页 Anhui Medical and Pharmaceutical Journal
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  • 1Kofod H, Euhlendorff J. Effect of repaglinide on insulin release in isolated islets of Langerhans is unaffected by metabolic stess induced by dinitrophenol. EurJ Endocrinol, 1995;132(suppl 1):14
  • 2Malaisse WJ. Stimulation of insulin release by non-sulfonylurea hypoglicemic agents: the meglitinide family. Horn metab Res, 1995;27: 263
  • 3Gromada J. Effects of the hypoglicemic drugs repaglinide and glibenclamide on ATP-sensitive Potassium-channels and sytosotic calcium levels in beta TC3 cell and rat pancreatic beta cells. Diabetologia,1995;38:1025
  • 4Unson CG. Position 9 replacement analogs of glucagon uncouple biological activity and receptor binding. J Biol Chem, 1991;266:2763
  • 5Caroline MS, Markham A. Troglitazone . Drugs, 1997; 54 ( 1 ): 89-101
  • 6Mstsumoto K, Miyake S, Yano M et al. Increase of lipoprotein(a)with troglitazone. Lancet, 1997;350(9093): 1748~9
  • 7Adams M, Montague CT, Prins JB et al. Activators of peroxisome proliferatoractivated receptor gamma have depot-specific effects on human preadipocyte differentiation. J Clin Invest, 1997; 100 ( 12 ):3149~53
  • 8Inzucchi SE, Maggs DG, Spollett GR et al. Efficacy and metabolic effects of metformin and troglitazone in type Ⅱ diabetes mellitus. N Engl J Med, 1998;338(3) :867~72
  • 9Maggs DG, Buchanan TA, Burant CF et al. Mebabolic effects of troglitazone monotherapy in type 2 diabetes mellitus: A randomized,double-mind, placebocontrolled tria. Ann lntern Med, 1998; 128(3):176~85
  • 10Fujiwara T, Wada M, Fukuada K et al. Characterization of CS450, a new oral antidiabetic agent 2. Effects on glycemic control and pancreatic islet structure at a late stage of the diabetic syndrome in C57BL/KsJ-db/db mice. Metabolism, 1991;40:1213~8

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