摘要
本文探讨阴茎海绵体内注射前列腺素E1(PGE1)和罂粟碱 (PAP)联合用药筛选非血管性勃起功能障碍的剂量选择。对 2 0例勃起功能正常组和 2 5例非血管性勃起功能障碍组采用不同剂量注射 ,并用多普勒超声检测阴茎海绵体动脉收缩期最大流速 (PSV)和舒张期流速 (EDV)。结果 1.小剂量 (PGE110 μg+PAP7.5mg)联合用药就可明显增加阴茎血流 ,产生良好的勃起 ,与ICI前相比有显著差异 (P <0 .0 1) ;2 .增加剂量与小剂量注射相比阴茎血流稍有增加 ,但各组间无显著差异 (P >0 .0 5 ) ;3.小剂量联合用药未出现阴茎持续勃起和局部疼痛。作者认为小剂量联合用药对非血管性勃起功能障碍患者就能产生良好的阴茎血流 ,多普勒超声可客规地评价阴茎的血流参数 。
To study the dose of PGE 1 and papaverine (PAP) for screening non-vasculogenic erectile dysfunction by intracavernous injection (ICI).20 males with normal erctile function and 25 cases with non-vasavulogenic erectile dysfunction were measured the Peak Systolic Velocity (PSV) and End Diastolic Velocity (EDV) by doppler sonography.Results:(1)Small dose (PGE 1 10 μg-PAP7.5 mg)can effectively increase the penile blood and,bring good erection,it is very significant compared with the amount before ICI ( P <0.01);(2)Additive dose increase little flowing blood,it is non-significant compared with small dose ( P >0.05);(3)Combined using small dose did not bring local ache and priapism.The results showed that Combined use of small dose vascdilators.can bring out good hemodynamics in penils for non-vasculogenic erectile dysfunction.
出处
《中国男科学杂志》
CAS
CSCD
2001年第3期186-188,共3页
Chinese Journal of Andrology
