摘要
目的 :研究砂仁挥发油主要成分乙酸龙脑酯的药理作用。方法 :番泻叶导致小鼠腹泻实验 ,冰醋酸导致小鼠疼痛实验 ,小鼠胃排空实验以及家兔离体小肠内压实验。结果 :乙酸龙脑酯组小鼠湿粪数、扭体次数明显少于空白对照组 ,家兔离体小肠运动抑制率明显低于空白对照组 ,小鼠胃排空率与空白对照组相比无显著性差异。结论 :乙酸龙脑酯有显著抑制番泻叶所致小鼠腹泻。
OBJECTIVE:To study pharmacological effects of bornyl acetate, the main ingradient of Amomum villosum volatile oil. METHODS:The experiments included diarrhea caused by Folium Sennae, pain caused by acetic acid, empty of mice stomach and inner pressure of rabbits' small intestine. RESULTS: Mouse's wet excrement numbers, writhe numbers and restrain rates of rabbit's small intestine in the bornyl acetate group were obviously less than that in the negative group, however, empty rates of mouse's stomach had no obvious different with the negative group.CONCLUSION:Bornyl acetate had obvious functions as relieving pain, antidiarrhea and restaining movements of small intestine smooth muscle.
出处
《华西药学杂志》
CAS
CSCD
2001年第5期356-358,共3页
West China Journal of Pharmaceutical Sciences
关键词
砂仁
乙酸龙脑酯
药理作用
挥发油
Amomum villosum
Bornyl acetate
Pharmacological effects
