摘要
目的 :探讨肌肉注射曲马多对硬膜外麻醉后寒战的预防效果。方法 :选择 6 0例准备在硬膜外麻醉下行下腹部、下肢或脊柱手术的成年患者 ,随机分为三组 (每组 2 0例 ) :肌注曲马多和氟哌啶组 (TD组 )、单纯氟哌啶组 (D组 )和对照组 (C组 )。于硬膜外注药前 30 min TD组肌注曲马多 1.5 mg.kg- 1和氟哌啶 5 m g;D组肌注氟哌啶 5 mg;C组肌注 2 m l的生理盐水。观察麻醉及手术过程中寒战的发生率、寒战的严重程度及寒战发生前后体温变化。结果 :寒战发生率 TD组为 5 % ,D组和 C组分别为 2 5 %和 35 % ,TD组与 C组比较差异有显著性 (P<0 .0 5 )。TD组嗜睡发生率较高 ,但无统计学意义。结论 :曲马多有助于预防低位硬膜外麻醉后寒战 。
Objective:To study whether intramuscular injection with tramadol can prevent shivering under epidural anesthesia. Methods:60 elderly patients operated on lower abdomen, lower limb and vertebral column under epidural anesthesia, were randomly divided into three groups:group TD(n=20), group D(n=20)and the control group (group C,n=20).The patients in group TD were injected intramuscularly with tramadol 1.5 mg.kg -1 and droperidole 5 mg; in group D, droperidole 5mg and those in group C were given 2 ml of saline 30 minutes before epidural anesthesia. All patients were observed to find out the rate and degree of shivering and the changes of tempreature before and after shivering in the course of anesthesia and operation. Results:The rates of shivering in group TD were 5 percent, and those in group D and group C were 25 percent and 35 percent, respectively. There was significant difference between group TD and group C( P <0.05).Conclusion:Tramadol could help to prevent shivering under epidural anesthesia, and droperidole could reduce some side effects of tramadol.
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2001年第3期242-244,共3页
Chinese Journal of Modern Applied Pharmacy
