摘要
翅子树(Pterospermum lanceaefolium Roxb)为梧桐科(Sterculiaceae)植物,民间用其叶作止血、抗菌药。初步药理试验表明,翅子树叶的乙醇提取物育较强的抑制大肠杆菌生长和缩短小白鼠凝血时间的作用。翅子树叶的化学成分尚未见报道。本文对其化学成分进行了研究,从酯溶部分中获得新三萜sterculin-A(Ⅰ)和2个已知的甾醇。
A new triterpene, sterculin-A (1), along with two known compounds, baurenyl acetate and β-sitosterol, were isolated from the ethyl acetate extracts of the leaves of P. lanicacfulunn Koxb. 1 is the colorless needle crystal, C30H50O2, m. p. 196- .197℃, [α]D25+15. 2(MeOH, c 0. 023), The structure of 1 was determined as cycloart-23Z-ene-3β, 25-diol on the basis of 1R, MS, 1H NMR, 13C NMR(DEPT), and COSY techniques.The NMR spectra of 1 in CDC13 was found changeable in several hours. Inspection of the changed NMR spectra reveals that a loss of a molecule of water has been occured due to the trace of acid contained in CDCl3. The structure of the product was assigned as cycloart-23E,25-dicne-3β-ol.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1993年第2期214-216,共3页
Chemical Journal of Chinese Universities
