摘要
设计一种新型的冷冻水浴型夹具,用于解决大鼠跟腱力学测试的问题。以SD大鼠肌肉-跟腱-跟骨为单元的样本随机分成A、B两组。A组:大鼠跟腱样本采用设计的新型水浴型冷冻夹具;B组:大鼠跟腱样本采用传统非水浴冷冻夹具。结果显示,在力学测试过程中,A组样本无一滑脱,跟腱处于生理活性状态;B组样本有一根滑脱,其他样本跟腱有明显被冷冻现象。A组样本平均最大应力、最大断裂点位移以及杨氏模量较B组差异均有统计学意义(P<0.05)。实验结果表明,新的冷冻水浴型夹具优于传统非水浴条件冷冻夹具,能够更好地模拟体内环境条件测试跟腱的力学性质。
This study was aimed to design a new, accurate and easy-to-use water bath cryo-jaw, and try to solve the problems met in small animals achilles tendon mechanical testing. The muscle-tendon-bony units were fixed in the clamps. SD rats achilles tendon were randomly divided into group A and B. Group A was tested by the newly de- signed water bath cryo-jaw, while group B was treated by non-water bath cryo-jaw. The mechanical tests revealed that non of the samples of the newly-designed water bath cryo-jaw in group A slipped and fell off, and the achilles tendons were in a physiologically active state, but one of the group B samples slipped and fell off, and the others had the frozen phenomenon obviously. The maximum stress, fracture displacement and Young＇s modulus of the rats in group A were significantly different compared to those in group B （P〈0.05）. In conclusion, the new water bath cryo-jaw has more advantages than traditional ones. It exhibits a good simulation in vivo in the environmental condi- tions for testing the mechanical properties of the achilles tendon.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2014年第3期678-681,共4页
Journal of Biomedical Engineering
基金
高等学校学科创新引智计划资助项目(国家"111计划")(B06023)
国家自然科学基金资助项目(11032012
31270990)
新世纪优秀人才支持计划资助项目(NCET-10-0879)
重庆大学大型仪器设备开放基金资助项目
关键词
冷冻水浴型夹具
跟腱
力学拉伸测试
应用
frozen water bath Cryo-jaw
achilles tendon
mechanical stretch test
application
