摘要
目的探讨布地奈德吸入治疗在新生儿肺炎中的应用效果。方法将80例肺炎新生儿采用随机数字表法分为观察组和对照组,每组40例。两组均以常规治疗为基础,对照组雾化吸入氨溴索治疗,观察组在对照组的基础上吸入布地奈德,比较两组的临床疗效。结果观察组的总有效率为85.0%显著高于对照组的70.0%(P<0.05)。观察组的鼻阻、气促、肺啰音消失以及住院时间均显著少于对照组(P<0.05)。观察组治疗后的IL-6、TNF-α水平显著低于对照组(P<0.05)。结论布地奈德雾化吸入能够提高新生儿肺炎的疗效,显著改善临床症状,降低患儿的炎性因子水平。
Objective To observe the curative effect of budesonide inhalation therapy on neonatal pneumonia. Methods Eighty neonatal pneumonia cases were randomly divided into the observation group and the control group, each composed of 40cases. Cases in two groups were given the conventional treatment, those in control group were treated with aerosol inhalation ofambroxol and that of the observation group were based on the treatment of control group, treated with inhaled budesonide. Thenthe clinical effects between two groups were compared. Results The total effective rate in the observation group was 85%,significantly higher than that of 70% in the control group（P〈0.05）. Disappearance time of nasal obstruction, shortness ofbreath, pulmonary rales and duration of hospital stay in the observation group were significantly less than those in the controlgroup（P〈0.05）.IL-6, TNF- α levels after treatment in the observation group were significantly lower than those in the controlgroup（P〈0.05）.Conclusion Budesonide inhalation can improve therapeutic effect of neonatal pneumonia and reduce thelevel of inflammatory factors in children
出处
《中国热带医学》
CAS
2014年第4期488-489,500,共3页
China Tropical Medicine
关键词
雾化吸入
布地奈德
新生儿肺炎
疗效
炎性因子
Atomization inhalation
Budesonide
Neonatal pneumonia
Curative effect
Inflammatory factor
