摘要
目的探讨不同暴露环境对男性官兵生殖健康的影响。方法 2013年8—9月选择某部男性志愿者400人,按照暴露环境不同分为未暴露组(n=220)、电离辐射组(n=35)、电磁辐射组(n=21)、有毒有害化学试剂组(n=73)、高温组(n=18)、高湿组(n=10)、高原组(n=10)、高噪声组(n=13)。对被调查官兵进行男科检查,对精子密度、活力、活率、形态学及DNA损伤进行测定分析,对各暴露组与未暴露组精液常规检查指标进行比较。结果 400名官兵睾丸体积略大于正常值,其余男科检查指标均正常。精液体积、精子总数、精子浓度、总活力[前向运动(PR)精子+非前向运动(NP)精子]、PR精子比率、存活率、正常形态精子比率、pH值、精子液化时间均正常。对精液异常结果进行分析,显示异常程度远低于笔者所在医院门诊异常水平。精子核DNA碎片测定结果显示,400名官兵红色荧光强度及红色荧光强度/总荧光强度值均正常。各暴露组精液质量均不同程度地低于未暴露组(P<0.05)。结论该部男性总体精液质量良好,暴露环境对精液质量有一定的影响。
Objective To explore the effects of different exposure environment on reproductive health of officers and soldiers. Methods From 2013 August to September, 400 male volunteers in a PLA unit were divided into different groups according to different exposure environment：unexposed group （ n=220 ） , ionizing radiation group （ n=35 ） , e-lectromagnetic radiation group （n=21）, poisonous and harmful chemicals group （n=73）, high temperature group （n=18）, high humidity group （n=10）, plateau group （n=10） and high noise group （n=13）. Values of sperm counts, motility of sperm, motility rate, morphology analysis and sperm DNA injury in all groups were detected. Seminal indexes of routine examination in all exposure environment groups were compared with that in unexposed group. Results The testicular volume of each of 400 officers and soldiers was slightly higher than the normal value, and the rest indicators were normal. Values of semen volume, total sperm number, sperm concentration, total activity [ prorsad （ PR） ＋ the non-prorsad （ NP） sperm movements] , PR sperm ratio, survival rate, percentage of normal morphology sperm, pH and semen liquefaction time were normal. Abnormal results of semen analysis showed that the abnormal degree of male volun-teers was obviously lower than of the outpatients. DNA fragments determination of sperm nuclear showed that red fluores-cence intensity and the value of red fluorescence intensity /total fluorescence intensity in the 400 officers and soldiers were normal. The semen qualities of exposed groups were worse in different degrees than that of unexposed group （P〈0. 05）. Conclusion Semen qualities of officers and soldiers in the unit are good in general, and exposed environ-ment has a certain influence on the semen quality.
出处
《解放军医药杂志》
CAS
2014年第5期68-71,共4页
Medical & Pharmaceutical Journal of Chinese People’s Liberation Army
基金
军队临床高新技术重大项目(2010gxjs003)
关键词
军事人员
精液分析
精液检测指标
Military personnel
Semen analysis
Seminal fluid detection parameter
