摘要
目的:探讨肝硬化并自发性腹膜炎中医证型与客观指标的相关性,为肝硬化并自发性腹膜炎辨证客观化提供依据。方法:将29例肝硬化并自发性腹膜炎患者按中医辨证标准进行辨证分型,同时检测患者肝功能ALT、AST、TBil、Alb、前白蛋白(PA)、血清总胆固醇(Tch)、凝血酶原时间(PT)、血常规、腹水常规及生化、血清C反应蛋白(CRP)水平,分析水湿内停证、湿热蕴结证、肝肾阴虚证、脾肾阳虚证与上述指标的关系。结果:血清TBil湿热蕴结证较水湿内停证明显升高,差异有显著性意义(P<0.05);腹水中性粒细胞比率(%)水湿内停证低于湿热蕴结证,差异有显著性意义(P<0.05);血清/腹水蛋白梯度湿热蕴结证低于肝肾阴虚证、水湿内停证,差异有显著性意义(P<0.05);血清CPR湿热蕴结证证明显高于水湿内停证,差异有显著性意义(P<0.05)。结论:肝硬化并自发性腹膜炎血清TBil、腹水中性粒细胞比率、血清/腹水蛋白梯度及血清CPR等指标的异常变化与中医证型之间存在一定的相关性。湿热蕴结证的感染较其他3种证型更为严重。
Objective： To explore the correlation between TCM syndrome type and objective index of spontaneous bacterial peritonitis in patients with liver cirrhosis , and provides the basis for the objectification of syndrome differentiation of spontaneous bacterial peritonitis in patients with liver cirrhosis. Methods： The syndrome differentiation of 29 patients of spontaneous bacterial peritonitis in patients with liver cirrhosis was performed standards for TCM syndrome type, liver function patients with ALT, AST, TBil, Alb, prealbumin （ PA）, serum total cholesterol （ Tch）, prothrombin time （ PT）, blood routine, biochemical, as- citesand serum C reactive protein （CRP） level were detected, relationship between syndrome of internal stagnation of fluid-damp- ness, stagnancy of warm-heat, liver kidney Yin deficiency, spleen kidney Yang deficiency and the index were analysed. Results ： Serum TBil of stagnancy of warm-heat group than internal stagnation of fluid-dampness group was significantly increased, with sig- nificant difference （ P 〈 0. 05 ） ; granulocyte ratio （ % ） with internal stagnation of fluid-dampness group was less than that of stag- nancy of warm-heat group, there was significant difference （ P 〈 0. 05 ） ; Serum ascites albumin gradient of stagnancy of warm- heat group than liver kidney Yin deficiency group, internal stagnation of fluid-dampness group, there was significant difference （P 〈 0. 05 ） ; serum CPR of stagnancy of warm-heat group was significantly higher than that of internal stagnation of fluid-damp- ness group, with significant difference （ P 〈 0.05 ） . Conclusion： There is a correlation between the change of serum TBil. granulocyte ratio （ % ） with internal stagnation, serum ascites albumin gradient, serum CPR of spontaneous bacterial peritonitis in patients with liver cirrhosis and TCM syndrome type. stagnancy of warm-heat group than the other three groups of infection is
出处
《中西医结合肝病杂志》
CAS
2014年第2期80-82,共3页
Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
基金
武汉市卫生局资助课题(No.WH11D21)
关键词
肝硬化
自发性腹膜炎
中医证型
liver cirrhosis
spontaneous bacterial peritonitis
TCM syndrome type
