摘要
目的评价中西医联合治疗阿尔茨海默病的疗效是否优于单一疗法。方法计算机检索CNKI、Wanfang、VIP数据库,纳入所有关于阿尔茨海默病/老年痴呆的随机对照试验,并对纳入文献进行质量评价。数据统计分析采用RevMan5.0软件进行。结果共纳入15个随机对照试验(RCT),其中对照组为单纯服用西药的RCT为13个,患者共计937例;对照组为单纯服用中药的RCT为2个,患者共计87例。Meta分析结果显示:与对照组比较,中药和西药联合治疗阿尔茨海默病的疗效优于任一单一疗法。结论中西医联合治疗阿尔茨海默病的疗效优于单一中药或西药疗法。
Objective To compare the effect of combined Chinese and Western medicine versus single therapy in treatment of Alzhei- mer＇ s disease. Methods By searching CNKI, Wanfang, VIP databases, the randomized controlled trials （RCTs） about Alzheimer disease were included. The quality of the articles was assessed. The data was input and analyzed by RevManS. 0 software. Results Fifteen randomized controlled trials（RCTs） met the inclusion criteria, including 13 RCTs （973 patients） with Western medicine as control group, and 2 RCTs （87 patients） with Chinese herb as control group. Meta analysis showed that the efficacy of combined Chi- nese and Western medicine was better than that of Chinese herb or Western medicine alone. Conclusion The curative effect of com- bined Chinese and Western medicine in treatment of Alzheimer＇ s disease is better than that of single therapy.
出处
《山西医科大学学报》
CAS
2014年第3期209-212,共4页
Journal of Shanxi Medical University
关键词
中西医结合
阿尔茨海默病
META分析
combined therapy of Chinese and Western medicine
Alzheimer＇ s disease
meta analysis
