摘要
目的 探讨中国华南地区胃癌临床病理特点,为胃癌的诊治提供基础数据.方法 收集中山大学附属第一医院1994年8月至2012年7月来自华南地区胃癌根治术病例共1 879例,回顾性分析性别、年龄、肿瘤部位、WHO组织学分型和分级、pTNM分期等各项因素,总结患者的临床与病理特点.结果 本组患者男性多于女性,比例为2.08∶1,但在40岁前,女性多于男性（x2=77831,P=0.000）；60岁以上为高发年龄段（46.0％）；好发部位依次为胃窦（45.7％）、胃体（26.3％）和贲门（20.1％）；常见的WHO组织学类型是管状或乳头状腺癌（81.5％）、印戒细胞癌（11.0％）；常见的组织学分级为低分化癌（67.7％）；pTNM分期多为Ⅲ（40.5％）和Ⅳ（26.5％）期.结论 中国华南地区胃癌男性多于女性,但在40岁前,女性多于男性,胃窦好发,腺癌最常见,多数为晚期病例.
Objective To investigate the clinicopathological features of gastric cancer in Southern China,and provide a base of research and therapy for gastric cancer.Methods A total of 1 879 cases of gastric cancer with radical gastrectomy from Southern China were collected from August 1994 to July 2012.Analyze and summarize the characters of gender,age,tumor location,WHO histopathologic type and grade,pTNM stage and family history,retrospectively.Results Among all cases,male to female ratio was 2.08：1,while female was more than male before 40 years （x2 =77.831,P =0.000）.Cases aged over 60 years had a highest incidence of gastric cancer （46.0%）,with predilection of sinus （45.7%）,body （26.3%） and cardia （20.1%）.The common WHO histopathologic types were tubular or papillary adenocarcinoma （81.5%） and signet ring cell carcinoma （11.0%）.Most patients were at Ⅲ or Ⅳ stage on pTNM staging （40.5% and 26.5%）.Conclusions Gastric cancer in Southern China has a predilection on male,while female is more than male before 40 years.Gastric sinus and adenocarcinoma is most common.Most patients are diagnosed at advanced stages.
出处
《中华外科杂志》
CAS
CSCD
北大核心
2014年第3期168-170,共3页
Chinese Journal of Surgery
关键词
胃肿瘤
回顾性研究
人种群
Stomach neoplasms
Retrospective studies
Ethnic groups
