摘要
目的探讨肌红蛋白（MYO）检测在急性心肌梗死（AMI）早期诊断中的临床意义。方法选择2013年l～10月确诊为AMI的50例患者作为观察组，选择同期50例健康体检者作为对照组，同时测定入选者的MY0、肌酸激酶（CK）及肌酸激酶同工酶（CK-MB）水平，并行心电图检查，对结果进行统计学分析。结果排除基线水平混杂影响，观察组患者MY0、CK和CK—MB水平均显著高于对照组，差异有统计学意义（P〈0．01）。胸痛早期组（0—6h）患者MY0水平显著高于胸痛中、晚期组（〉6～24h、〉24～48h）患者，差异有统计学意义（P〈0．05），而胸痛早、中、晚期组患者CK和CK—MB水平比较．差异无统计学意义（P〉0．05）。胸痛早期患者MY0阳性检出率为78．0％，高于心电图、CK和CK-MB阳性检出率（60．O％、56．0％、46．0％），差异有统计学意义（P〈0．05）。结论MYO可作为早期诊断AMI较理想的指标，具有出现时间早、阳性检出率高等特点，能为病情鉴别、治疗以及预后等提供可靠依据。
Objective To explore the clinical significance of myoglobin（MYO） testing to the acute myocardial infarction （AMI）. Methods A total of 50 patients, who were diagnosed as AMI from January to October 2013, were selected as experimen- tal group, simultaneously, 50 healthy respondents were taken as control group. All the respondents were tested on the levels of MYO, creatine kinase （CK） and CK-MB, checked by electrocardiography （ECG）, and the results were analyzed statistically. Re- suits Except the effect of baseline confounding, the levels of MYO, CK and CK-MB in observation group were obviously higher than those in the control group with statistical significant difference （P〈0.01）. Compare with the medium and advanced stage patients （〉6-24 h, 〉24-48 h）, there was obvious improvement of MYO level in the early stage patients （0-6 h） with statistically signifi- cant difference （P〈0.05）, but the comparison of CK level and CK-MB level of patients in early, medium and advanced stage had no statistically significant difference （P〉0.05）. The positive rate of MYO in early stage patients with chest pain was 78.0%, which was obviously higher than that of ECG, CK and CK-MB （60.0%,56.0% ,46.0% ）, and the difference had statistical significance （P〈 0.05）. Conclusion MYO is an ideal indicators for the diagnosis of AMI,it has characteristics of early appearance, high positive detection rate, and it can provide reliable basis for disease identification, treatment and prognosis.
出处
《现代医药卫生》
2014年第6期828-829,共2页
Journal of Modern Medicine & Health
关键词
肌红蛋白
肌酸激酶
心电描记术
肌酸激酶同工酶
急性心肌梗死
Myoglobin
Creatine Kinase
Electrocardiography
Creatine Kinase isoenzyme MB
Acute Myocar- dial Infarction
