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FIB CLAUSS法和PT-衍生法在ACL-TOP血凝仪上的应用比较 被引量:3

Comparison between the Amplification of CLAUSS and PT-derived Method to Test FIB on the ACL-TOP
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摘要 目的对ACL-TOPPT衍生法和CLAUSS法的测定结果进行比较,为两种方法的合理应用提供依据。方法应用PT-衍生法和CLAUSS法分别测试纤维蛋白(fibrinogen,FIB),用SPSS软件进行t检验比较两组数据的差异,用相关系数r分析两组数据相关性。结果PT-衍生法FIB结果为:1~2g/L时,差异无统计学意义(P〉0.05),r=0.894;2~5g/L时,差异无统计学意义(P〉0.05),r=0.961;5~6g/L时,差异有统计学意义(P〈0.05),r=0.040;6~7g/L时,差异有统计学意义(P〈0.05),r=0.180。结论PT-衍生法测定结果为1~5g/L时,两种方法相关性好,可直接用PT-衍生法报FIB的结果。当PT-衍生法的测定结果〈1g/L或〉5g/L时,应采用CLAUSS法。 Objective To compare the test results of ACL-TOP PT derivative method and CLAUSS, and supply reference for reasonable application of the two methods. Methods Fibrinogen (FIB) were tested by PT-derived method and CLAUSS method respectively. By using SPSS software, t-test was used to compare the results between two groups and the correlation coefficient r was used to measure the correlation. Results When FIB tested by PT derivative method was 1-2 g/L, the difference between two methods was not statistically significant (P~{I. t}5) and r = {I. 894. When it was 2-5 g/L, the difference was not statistically significant (P~〉0. 05) and r= 0. 961. When it was 5-6 g/L, the difference was statistically significant (P~{I. I)5) and r = 0.040. When it was 6-7 g/L, the difference was statistically significant (P 〈11. 05) and r= 1/. 180. Conclusion PT derivative method is appropriate for the test of FIB in 1-5 g/L when there is no statistically significant difference compared with GLAUSS methods and their correlation is good. When the result of PT derivative method is 〈1 g/L or 〉5 g/L, CLAUSS method should be used.
出处 《华南国防医学杂志》 CAS 2014年第1期60-61,73,共3页 Military Medical Journal of South China
关键词 CLAUSS法 纤维蛋白 PT-衍生法 CLAUSS method Fibrinogen PT derived method
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