期刊文献+

脉压与C反应蛋白、血尿酸和血清总胆红素水平的相关性探讨 被引量:3

在线阅读 下载PDF
导出
摘要 目的探讨原发性高血压病患者脉压(PP)与C反应蛋白(CRP)、血尿酸(UA)、血清总胆红素(T-BIL)水平的相关性。方法将120例原发性高血压病患者按照脉压的不同,分为PP1组(脉压≤40 mmHg)、PP2组(脉压40 mmHg^60 mmHg)、PP3组(脉压≥60 mmHg),另选取50例健康者作为对照组,分别测定CRP、UA和T-BIL水平。结果 (1)高血压病患者CRP、UA、TBIL水平与对照组比较,差异有统计学意义(P<0.05);不同脉压组间CRP、UA、T-BIL水平差异亦有统计学意义(P<0.05或P<0.01);(2)脉压与CRP、UA水平正相关,与T-BIL水平负相关。结论 CRP、UA和T-BIL水平与脉压密切相关,3者是反映原发性高血压机体代谢紊乱的重要指标,可评估高血压病变的严重程度。
作者 代晓明 刘莉
出处 《黑龙江医学》 2014年第1期6-7,共2页 Heilongjiang Medical Journal
  • 相关文献

参考文献13

  • 1Domanski M J,Sutton Tyrrell K,Mitchell G F. Deter minants and prognostic information provided by pulse pressure in patients with coronary artery disease undergoing revascularization.The Balloon Angioplasty Revascularization Investigation(BARI)[J].American Journal of Cardiology,2001,(06):675-679.
  • 2Erdogan D,Gullu H,Yildirim E. Low serum bilirubin levels are independently and inversely related to impaired flow-mediated vasodilation and increased carotid intima-media thickness in both men and women[J].ATHEROSCLEROSIS,2006,(02):431-437.
  • 3王文.第六届国际高血压及相关疾病学术研讨会纪要[J].高血压杂志,2004,12(6):490-491. 被引量:34
  • 4Kulah E,Duraun A,Acikgoz S. The relationship of target organ damage and 24-hour ambulatory blood pressure monitoring with vitamin D receptor gene fok-I polymorphism in essential hypertension[J].KIDNEY AND BLOOD PRESSURE RESEARCH,2006,(06):344-350.
  • 5Franklin S S,Gustin W,Wong N D. Hemodynamic patterns of age-related changes in blood pressure[J].CIRCULATION,1997,(01):308-315.
  • 6Venugopal S K,Devaraj S,Yuhanna I. Demonstration that C-reactive protein decreases eNOS expression and bioactivity in human aortic endothelial cells[J].CIRCULATION,2002,(12):1439-1441.
  • 7Krishnan E,Kwoh C K,Schumacher H R. Hyperuricemia and incidence of hypertension among men without metabolic syndrome[J].HYPERTENSION,2007,(02):298-303.
  • 8Forman J P,Choi H,Curhan G C. Uric acid and insulin sensitivity and risk of incident hypertension[J].Archives of Internal Medicine,2009,(02):155.
  • 9Meisinger C,Koenig W,Baumert J. Uric Acid levels are associated with all-cause and cardiovascular disease Mortality independent of systemic inflammation in men from the general population the MONICA/KORA Cohort study[J].Arteriosclerosis Thrombosis and Vascular Biology,2008,(06):1186-1192.
  • 10Kawamura K,Ishikawa K,Wada Y. Bilirubin from heme oxygenase-1 attenuates vascular endothelial activation and dysfunction[J].Arteriosclerosis Thrombosis and Vascular Biology,2005,(01):155-160.

二级参考文献8

  • 1朱昀,周玲,张帆,张福春,郭静萱.老年高血压病患者左心室肥厚危险因素分析[J].中华老年心脑血管病杂志,2005,7(2):91-93. 被引量:5
  • 2Staessen JA,Li Y,Thijs L, et al . Blood pressure reduction and cardiovascular prevention: an update including the 2003-2004 secondary prevention trials[J].Hypertens Res, 2005,25 : 385- 407.
  • 3Viazzi F, Leoneini G, Parodi D, et al . Pulse pressure and subclinical cardiovascular damage in primary hypertension [J]. Ncphrology Dialysis Transplantation,2002,17 : 1779-1785.
  • 4Domanski MJ,Sutton-Tyrrell K, Mitchell GF, et al . Determinants and prognostic information provided by pulse pressure in patients with coronary artery disease undergoing revascularization. The Balloon Angioplasty Revascularization Investigation (BARI) [J]. Am J Cardiol, 2001,87 : 675-679.
  • 5Chin SP, Chung NAY, Gibbs CR, et al . Vascular endothelial growth factor and soluble P-selectin in acute and chronic heart diseases[J]. Am J Cardiol, 2002,90 : 1258-1260.
  • 6Pearson TA, Mensah GA, Alexander RW, et al . Markers of inflammation and cardiovascular disease, application to clinical and public health practice: a statement for healthcare professionals from the centers for disease control and prevention and the American Heart Association[J].Circulation, 2003, 107 : 499-512.
  • 7Kingwell BA, Waddell TK, Medley TL, et al. Large artery stiffness predicts ischemic threshold in patients with coronary artery disease[J].J Am Coll Cardiol, 2002,40 : 773-779.
  • 8周北凡,刘小清,武阳丰,李义和,杨军,饶栩栩,赵连成,麦劲壮,李莹,郭成业,田秀珍,石美玲,于学海,邓木兰.我国中年人群脉压对于心血管病事件发病的预测价值[J].中华心血管病杂志,2002,30(11):687-691. 被引量:76

共引文献36

同被引文献38

引证文献3

二级引证文献23

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部