摘要
目的 探讨广西壮族自治区肝吸虫病的高发流行特点及其超声诊断价值.方法 选择2010年1月～2013年1月带有疑似肝吸虫感染的B超单来广西壮族自治区疾病预防控制中心门诊就诊的患者共455人作为调查对象,根据他们来自的家乡分为有食生鱼片风俗习惯的地区（横县、武鸣和南宁吴圩镇,A组）,无生鱼片风俗习惯的地区（宾阳、贵港、桂平,B组）.记录调查对象的基本情况,确定当地与肝吸虫病感染有关的危险因素.结果 455例对象中,感染219例（47.5％）.A、B组肝吸虫人群感染总阳性率比较,差异有统计学意义（x2=13.086,P＜ 0.05）.不同年龄、职业、文化程度间感染阳性率比较,差异有统计学意义（x2=10.26、9.88、11.92,P＜0.05）.不同性别间感染阳性率差异无统计学意义（x2=3.09,P＞0.05）.多因素非条件Logistic分析显示,年龄越大,感染风险越大（P＜0.05）,而具有相关医学背景、文化程度高可降低感染的风险（P＜ 0.05）.两组门脉主干内径、脾脏厚度、门脉平均流速、肝动脉血流搏动指数、肝血管指数比较,差异均有统计学意义（P＜0.05）.结论 年龄大、缺乏相关医学背景、文化程度低都将增加感染的风险.超声检测可及时发现门脉及肝动脉血流情况的异常,对早期诊断肝吸虫病并发肝硬化有积极意义.
Objective To study the high prevalence epidemic characteristics and the ultrasound diagnostic value of clonorchiasis in Guangxi Zhuang Autonomous Region. Methods 455 cases suspected with liver fluke infection detected by B uhrasonic in Centers for Disease Control and Prevention Clinic for treatment from January 2010 to January 2013 were chosen as the research object, and were divided into group A with fresh sashimi customs areas （Hengxian, Wum ing and Wuxu Town of Nanning）, and group B without fresh sashimi customs areas （Binyang, Guigang, Guiping ）. The basic situation of the investigation were recorded. Local risk factors associated with liver fluke disease infection were determined. Results 455 cases of object, 219 cases （47.5%） had clonorchiasis. The total infection positive rate between the two groups had statistically significant （X2=13.086, P 〈 0.05）. The comparison of infection positive rates among different ages, occupation, cultural levels had statistically significant （x2=10.26, 9.88, 11.92, P 〈 0.05）. There was no statistically significant difference between the sexes （X2=3.09, P 〉 0.05）. Multi-factor unconditioned Logistic analysis showed that the age for older would increase the risk of infection, and relevant medical background and the higher level of education would decrease the risk of infection （P 〈 0.05）. The comparison of portal vein diameter, spleen thickness, the average flow velocity of portal vein and hepatic artery blood flow pulsation index, hepatic vascular index showed in two groups had statistical significance （P 〈 0.05）. Conclusion The older, without related medical background, lower level of education will increase the risk of infection. Ultrasonic testing can find portal vein and hep atic artery blood flow abnormalities timely, it has a positive meaning of the early diagnosis of liver fluke disease com plicated with cirrhosis of the liver.
出处
《中国医药导报》
CAS
2014年第5期109-111,共3页
China Medical Herald
关键词
肝吸虫病
高发流行特点
超声诊断
广西壮族自治区
Liver fluke disease
High prevalence
Ultrasound diagnosis
Guangxi Zhuang Autonomous Region
