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细胞块切片免疫组化染色在胸腔积液病理诊断中的应用价值 被引量:15

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摘要 目的探讨细胞块切片免疫组化染色在胸腔积液病理诊断中的应用价值。方法对该院收集82例胸腔积液患者,分别行常规细胞涂片和细胞块切片联合免疫组化染色检测,比较两种方法对胸腔积液病理的诊断价值。结果细胞块切片结合免疫组化阳性率为100%,明显高于常规细胞学涂片的阳性率56.10%,差异有统计学意义(P<0.01);CEA、CK7是腺癌较为特异性的抗体,而CR是间皮性肿瘤细胞较为特异性的抗体,各抗体在腺癌细胞和间皮细胞均有交叉表达。结论胸腔积液细胞切片在恶性胸腔积液的诊断中重要的意义,联合免疫组化染色可有效鉴别肺腺癌和恶性间皮瘤,为临床的治疗提供了理论参考,值得临床广泛推广和应用。
出处 《中外医疗》 2014年第1期179-179,181,共2页 China & Foreign Medical Treatment
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