摘要
目的：探讨采用BIS监测下肝移植手术三个分期丙泊酚用量变化情况。方法：选择笔者所在医院肝移植手术患者18例，均采取静息复合麻醉方式，脑电双频指数维持在35～50，观察三个分期丙泊酚用药的剂量与尿量。结果：无肝期与新肝期的丙泊酚用量显著低于无肝前期，差异有统计学意义（P〈0．05）。无肝期尿量与无肝前期和新肝期比较显著减少，差异有统计学意义（尸〈0．05）。结论：无肝期的肝脏功能缺失与新肝移植的功能状态是主要影响丙泊酚的重要因素，肾脏的排泄功能与血液的稀释对于丙泊酚药效也有一定的影响。
Objective： To investigate the propofol dosage changes in three installments of BIS monitoring liver transplant.Method： 18 patients with Liver transplant surgery in author＇s hospital were selected, taken resting anesthesia way, bispectral index remained at 35-50, observed propofol dose of medication and urine in three installments.Result： The new dose of propofol in none of the liver and the hepatic phase were significantly lower than those in without liver early, the difference was statistically signifieant（P〈0.05）.The urine in none of the liver was significantly reduced compared with those in without liver early and the hepatic phase, the difference was statistically significant（P〈0.05）.Conclusion： No loss of function of liver of liver function with the new status of liver transplantation is the major intluence of prepofol important factor, renal excretory function and blood dilution for the efficacy of propofol also has a certain impact.
出处
《中外医学研究》
2013年第35期129-130,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
