摘要
目的：探讨血清总胆固醇（TC）的异常改变与冠心病痰瘀证候的关系。方法：应用Meta分析法对10篇文献中冠心病＂痰浊证＂、＂血瘀证＂患者与＂正常对照者＂的TC含量进行综合分析。结果：TC含量显示,血瘀证患者比正常对照者标准差高0.99~2.426倍,Total合并=0.71,Total合并95%置信区间为0.16~1.25;痰浊证患者比正常对照者标准差高1.019~3.761倍,Total合并=1.05,Total合并95%置信区间为0.43~1.68。结论 ：冠心病患者血瘀证和痰浊证的TC含量与正常对照者比较存在显著差异,TC含量的异常改变可作为冠心病痰瘀辨证的客观指标之一。
This study was aimed to find out the relationship between the serum total cholesterol （ TC ） and coronary heart disease （ CHD ） of phlegm and blood stasis syndrome . Meta -analysis was used on the comprehensive analysis of ten research literatures on TC content of CHD patients with ＂phlegm-turbid syndrome＂, ＂blood-stasis syndrome＂ and ＂normal control .＂ The results showed that the content of TC was 0.99-2.426 times h igher standard deviation in the blood-stasis syndrome patients than in the normal control, Totalcombined = 0.71. And the 95% confidence intervals of Totalcombined was 0.16-1.25. And the content of TC was 1.019-3.761 times higher standard deviation in the phlegm-turbid syndrome than in the normal control, Totalcombined= 1 . 05 . And the 95% confidence intervals of Totalcombined was 0 . 43-1 . 68 . It was concluded that there were significant variations of TC content in CHD patients with blood-stasis and phlegm-turbid syndrome compared to normal control . Therefore , abnormal changes of TC content can be used as one of the objective CHD diagnostic criteria of phlegm and blood stasis syndrome .
出处
《世界科学技术-中医药现代化》
北大核心
2013年第6期1383-1387,共5页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
教育部高校博士点基金项目(优先发展领域)(20124323130001):冠心病血瘀证心肌细胞能量代谢网络模型的研究
负责人:袁肇凯
国家自然科学基金委面上项目(81273670):冠心病血瘀证心肌细胞能量代谢网络模型的研究
负责人:袁肇凯
江西省卫生厅中医药科研计划(2012A060):动脉粥样硬化"痰瘀"演变的内在机制研究
负责人:喻松仁
关键词
冠心病
证候
血清总胆固醇
META分析
Coronary heart disease, syndrome, serum total cholesterol, meta-analysis
