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胰岛素泵治疗期间糖尿病患者夜间低血糖的危险因素 被引量:9

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摘要 目的探讨2型糖尿病(T2DM)患者接受胰岛素泵治疗期间发生夜间低血糖的影响因素。方法选择100例发生夜间低血糖的T2DM患者作为病例组;同期住院未发生的T2DM患者102例作为对照组。所有研究对象均按糖尿病患者的常规饮食和运动指导,并接受胰岛素泵治疗。收集性别、年龄、病程、腰围、体重指数(BMI)、糖尿病并发症等基本信息和糖化血红蛋白(HbA1c)、内生肌酐清除率(Ccr)、睡前血糖等生化指标。结果 BMI、腰围、Ccr、HbA1c和睡前血糖与T2DM患者胰岛素泵治疗期间发生夜间低血糖差异显著(P<0.05)。腰围越小、睡前血糖较低是T2DM患者胰岛素泵治疗期间发生夜间低血糖的危险因素(P<0.05)。BMI高是T2DM患者胰岛素泵治疗期间发生夜间低血糖的保护因素。结论夜间低血糖是多因素综合作用的结果。减少危险因素,及时调整治疗方案是防治夜间低血糖的关键。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2013年第22期5604-5605,共2页 Chinese Journal of Gerontology
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