摘要
目的:观察中西医结合治疗胃肠道肿瘤的临床疗效。方法:将120例患者按随机数字表法分为3组各40例。对照1组采用奥沙利铂加5-氟尿嘧啶治疗;对照2组采用参苓白术散加减治疗;观察组则采用中西医结合方法,给予对照1组联合对照2组方案治疗。观察3组患者的临床症状的缓解情况以及生活质量的变化情况,比较近期临床疗效以及不良反应的发生率。结果:观察组患者的临床症状的缓解情况以及生活质量的变化情况均明显优于对照1组、对照2组(P<0.05);观察组的近期治疗总有效率为92.50%,优于对照1组的70.00%、对照2组的67.50%(P<0.05);而观察组的不良反应发生率为12.50%,显著低于对照1组的35.00%(P<0.05);对照2组的不良反应发生率为15.00%,与现察组比较,差异无显著性意义(P>0.05)。结论:中西医结合治疗胃肠道肿瘤可缓解患者症状,提高生活质量,减少不良反应,疗效确切,安全性高,值得在临床上推广使用。
Objective： To observe the clinical efficacy and safety of integrated Chinese and western medical treatment for gastroenteric tumor. Methods： One hundred and twenty gastroenteric tumor pa- tients were evenly divided into three groups according to the random number table. Control group 1 was given western medicine of oxaliplatin and 5-fluorouracil, the control group 2 was treated with modified Shenling Baizhu Powder, and the observation group was given integrative treatment of oxaliplatin, 5-fluo- rouracil modified Shenling Baizhu Powder. We observed the remission of symptoms and quality of life in the three groups, and then compared the short-term clinical efficacy and the incidence of adverse reaction in the three groups. Results： The remission of symptoms and quality of life of the observation group were were significantly better than the two control groups（P 〈 0.05）, the short-term total effective rate in the observation group was 92.50%, significantly higher than 70.00% in control group 1 and 67.50% in the control group 2（P 〈 0.05）. The adverse reactions of the observation group was 12.50%, significantly lower than the 35.00% of control group 1（P 〈 0.05）. Compared with the observation group, the adverse reaction of the control group 2 was 15.00%（x^2=3.28） and the difference was insignificant（P 〉 0.05）. Conclusion. In- tegrated Chinese and western medical treatment is safe and effective for gastroenteric tumor through relieving the symptoms, increasing the quality of life and reducing the adverse reaction.
出处
《新中医》
CAS
2013年第12期124-126,共3页
New Chinese Medicine
关键词
胃肠道肿瘤
中西医结合疗法
临床疗效
不良反应
Gastroenteric tumor
Integrated Chinese and western medical therapy
Clinical efficacy
Adverse reaction
