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哺乳期乳腺炎临床分型及个体化治疗策略的探讨 被引量:37

Clinical classification of lactational mastitis and strategies of individualized therapy
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摘要 目的探讨哺乳期乳腺炎临床分型及个体化治疗效果和策略。方法回顾性分析了2006年7月至2011年8月本院收治的1650例哺乳期乳腺炎患者的临床资料,将其分为传统治疗组736例及个体化治疗组914例进行对比分析。计数资料用卡方检验,计量资料用两样本t检验。结果个体化治疗组治愈率为92.8%(849/914),症状缓解的平均时间为(1.86±1.97)d,回乳率为13.3%(122/914),脓肿形成率为7.2%(65/914),复发率为6.1%(56/914),均明显低于传统治疗组(P<0.01)。在传统治疗组,外周型乳腺炎患者的脓肿形成率(13.8%,59/427)和回乳率(42.4%,181/427)均低于中央型乳腺炎(51.0%,26/51;84.3%,43/51),差异有统计学意义(P<0.05);在个体化治疗组,外周型乳腺炎患者的脓肿形成率(5.9%,30/505)和回乳率(4.2%,21/505)显著低于中央型乳腺炎(25.9%,15/58;70.7%,41/58),差异有统计学意义(P<0.05)。结论对于哺乳期乳腺炎患者,应根据不同的临床分型,给予相应的个体化治疗,可以提高治愈率,减少回乳、复发及脓肿形成。 Objective To investigate the clinical classification of the lactational mastitis and the strategies of individualized therapy.Methods We retrospectively analyzed 1650 patients with lactational mastitis admitted in our hospital from July 2006 to August 2011.They were divided into two groups for comparison:the conventional therapy group (n =736) and the individualized therapy group (n =914).The numeration data were analyzed using chi-square test,measurement data using two-sanple t test.Results In the individualized therapy group,the cure rate was 92.8% (849/914),the average time of symptom relief (1.86± 1.97) d,milk regurgitation rate 13.3% (122/914),the rate of abscess formation (7.2%,65/914),and the recurrence rate(6.1%,56/914),which were significantly lower than those in the conventional therapy group (P<0.01).In the conventional therapy group,the rate of abscess formation (13.8%,59/427) and milk regurgitation rate (42.4%,181/427)in peripheral mastitis patients were significantly lower than those in the patients with central mastitis (51.0%,26/51 ;84.3 %,43/51 ; P<0.05).In the individualized therapy group,the rate of abscess formation (5.9%,30/505) and milk regurgitation rate (4.2%,21/505) in peripheral mastitis patients were significantly lower than those in the patients with central mastitis (25.9%,15/58 ;70.7%,41/58 ; P<0.05).Conclusion Based on the clinical classification,the individualized therapy should be given to lactational mastitis patients,which can improve the cure rate,reduce the milk regurgitation,recurrence and abscess formation.
出处 《中华乳腺病杂志(电子版)》 CAS 2013年第4期7-11,共5页 Chinese Journal of Breast Disease(Electronic Edition)
关键词 乳腺炎 哺乳期 临床分型 个体化治疗 Mastitis Lactation Clinical classification Individualized therapy strategy
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参考文献12

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