1VARGAS M, HORCAJADA J P, OBACH V, et al. Clinical con-sequences of infection in patients with acute stroke:Is it prime time for further antibiotic trials7 [J] Stroke,2006,37:461-465.
2HOWARD R J, SIMMONS R L. Acquired immunologic defi- ciencies after trauma and surgical procedures [ J ]. Surg Gyne- col Obstet, 1974,139:771-782.
3PRASS K, MEISEL C, HOFLICH C, et al. Stroke- induced im- munodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation [ J ]. Exp Med, 2003,198:725-736.
4VOGELGESANG A, GRUNWALD U, LANGNER S, et al. A- nalysis of lymphocyte subsets in patients with stroke and their influence on infection after stroke[J]. Stroke,2008,39:237-241.
5KLEHMET J, HARMS H, RICHTER M, et al. Stroke- induced immunodepression and post-stroke infections:lessons from the preventive antibacterial therapy in stroke trial [ J ]. Neuro- science ,2009,158 ( 3 ) : 1184-1193.
7OFFNER H, SUBRAMANIAN S, PARKER S M, et al. Experi- mental stroke induces massive, rapid activation of the peripher- al immune system [ J ]. Cereb Blood Flow Metab, 2006,26 : 654-665.
8KNUTSEN A P, FREEMAN J J, MUELLER K R, et al. Thy- mosinl alphal stimulates maturation of CD34 + stem cells into CD3 +4 + cell in an in vitro thymic epithelia organ coculture model [ J ]. Int J Immuopharmacol, 1999,21 ( 1 ) : 15-26.
9SILECCHIA G, GUARINO E, SINIBALDI- VALLEBONA P. Efficacy of repeated cycles of chemo-immunotherapy with thy- mosin alphal and interleukin-2 after intraperitoneal 5-fluorou- racil delivery [ J ]. Cancer Immunol lmmuother, 1999,48 ( 4 ), 172-178.
7Adrie C, Pinsky MR. The inflammatory balance in human sepsis[J]. Intensive Care Meal,2000,26(3):364 - 375.
8Paste G. Pathogenesis of metastatic disease:implications for current therapy and the development of new therapeutic strategies (paste)[J]. Cancer Trent Rep, 1986,70(8) :183 - 199.
9MUNOZ-PRICE L S, WEINSTEIN R A. Acinetobacter infection[J]. N Engl J Med,2008,258:1271-1281.
10SHORR A F. Review of studies of the impact on Gram-negative bacterial resistance on outcomes in the intensive care unit [ J ]. Crit Care Med,2009,37 : 1463-1469.
5YANG Y M, SHAO X H, ZHU J, et al. Risk factors and inci- dence of stroke and MACE in Chinese atrial fibrillation pa- tients presenting to emergency departments : a national wide da- tabase analysis [ J ]. Int J Cardio1,2014,173 (2) :242-247.
6SANTOS C O, CAEIRO L, FERRO J M, et al. A study of sui- cidal thoughts in acute stroke patients [ J ]. J Stroke Cerebro- vasc ,2012,21 (8) :749-754.
7GUPT K, PIPIOS I I, MILLER W J, et al. A population-based study of risk factors for stroke after carotid endarterectomy u- sing the ACS NSQIP database[ J]. J Surg Res,2011,167(2) : 182-191.
8PARK J M, CHO Y J, LEE K B, et al. Internet-based control recruitment for a case-control study of major risk factors for stroke in Korea : lessons from the experience [ J ]. J Stroke Ce- rebrovasc ,2014,23 (10) :2559-2565.
9Nguyen FN,Kar JK,Zakaria A,et al.Isolated central nervous system histoplasmosis presenting with ischemic pontine stroke and meningitis in an immune-competent patient. JAMA Neurol,2013,70(5):638-641.
10Harms H,Reimnitz P’Bohner G,et al.Influence of stroke localization on autonomic activation, immunodepression, and post-strokeinfection. Cerebrovasc Dis,2011,32(6):552-560.