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配合物Cd(pyzdc)(H_2O)_3的结构及其与DNA作用研究 被引量:1

Structure of the Complex Cd(pyzdc)(H_2O)_3 and Interaction with DNA
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摘要 在常温条件下,合成配合物Cd(pyzdc)(H2O)3(pyzdc为吡嗪-2,3-二羧酸),并对其结构进行表征.通过荧光光谱法和琼脂糖凝胶电泳法,研究配合物Cd(pyzdc)(H2O)3与DNA的作用机理.结果表明:此配合物能与DNA发生作用,并具备对DNA的切割能力. The complex Cd (pyzdc) (H20)3 was synthesized at room temperature, and characterized ( pyzdc = pyrazine-2,3-dicarboxylic acid). Mechanism of interaction with DNA was determined by fluo- rescent spectrometry and agarose gel electrophoresis. The results showed that the titled complex could in- teract with and cleave DNA.
出处 《沈阳化工大学学报》 CAS 2013年第3期193-196,208,共5页 Journal of Shenyang University of Chemical Technology
基金 国家自然科学基金项目(21171118) 辽宁省特聘教授资助计划和沈阳市重点实验室资助项目(F10-215-1-00)
关键词 镉(Ⅱ)配合物 晶体结构 荧光光谱法 琼脂糖凝胶电泳法 Cd ( II ) complex crystal structure fluorescent spectrometry agarose gel electro-phoresis
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