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胃肠间质瘤诊断及其预后相关危险因素研究进展 被引量:5

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摘要 胃肠间质瘤是一种最常见的起源于胃肠间叶组织的肿瘤,目前认为:其主要来源于Cajal细胞,主要发生于胃、小肠、结肠等部位;c-kit/PDGFRA基因突变导致组织酪氨酸激酶受体通路的激活是胃肠间质瘤发病的主要机理.胃肠间质瘤的比例约占所有胃肠道肿瘤的1%~3%,患者临床表现与肿瘤的发生部位、大小、恶性程度有关,通常表现为消化道出血、肠梗阻、腹痛等.
作者 刘伟 胡兵
出处 《现代临床医学》 2013年第5期395-397,共3页 Journal of Modern Clinical Medicine
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