摘要
目的探讨东北地区10年荨麻疹和湿疹患者常见的过敏原种类,为其治疗及预防提供依据。方法采用我科信息系统数据库资料,统计自2002年10月—2012年10月共计38 787例荨麻疹患者和24 483例湿疹患者血清中变应原特异性IgG检测结果并分析。结果 38 787例荨麻疹患者中有36 498例血清特异性IgG呈阳性(94.1%),前5位敏感食物依次为:牛奶(57.34%)、鸡蛋(41.66%)、虾(30.29%)、鳕鱼(24.58%)、螃蟹(20.02%);24 483例湿疹患者中有23 626例血清特异性IgG呈阳性(96.5%),前5位敏感食物依次为:螃蟹(62.27%)、牛奶(33.71%)、鸡蛋(29.42%)、大豆(22.79%)、鳕鱼(21.44%);荨麻疹患者对鸡蛋和牛奶的不耐受率随年龄增长逐渐降低,湿疹患者对螃蟹的不耐受率随年龄增长逐渐增高。结论东北地区10年荨麻疹和湿疹患者对常见食物的迟发型变态反应有一定规律,通过检测可及时发现不耐受食物并调节饮食结构,有利于临床症状的缓解。
Objective To explore the common allergens in patients with urticaria or eczema in northeast region of China during 10 years, so as to provide basis for their prevention and treatment. Methods Western blot was used for testing serum allergen-specific IgG in 38,787 cases of urticaria and 24,483 cases of eczema from October 2002 through October 2012. Results Specific IgG was positive in 36,498 of 38,787 cases of urticaria （94.1%）. The top five foods were milk （57.34%）, egg （41.66%）, shrimp （ 30. 2967o ）, cod （24.58%） and crab （20.02%） in turn. It was positive in 23,626 of 24,483 cases of eczema （96.5%）. The top five foods were crab （62.27%） , milk （ 33.71% ）, egg （29.42%） , soya bean （22.79%）, cod （21. 4467o ） in turn. In the patients with urticaria, the sensitive rates of egg and milk decreased with age, while in those with eczema that of crab gradually in- creased with age. Conclusion The delayed-type hypersensitivity is of regularity in the patients with urticaria or eczema in the Northeast of China in the recent 10 years. By detection, we can find out the sensitive food in time and adjust the diet structure, to mitigate the clinical symptoms.
出处
《临床军医杂志》
CAS
2013年第9期927-929,共3页
Clinical Journal of Medical Officers
