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胆管内支架联合化石利胆汤治疗较大胆总管结石的疗效观察 被引量:1

Clinical observation oncholedocholithiasis treated by bile duct stent combined with Huashi Lidan Decoction
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摘要 [目的]观察内镜介入联合化石利胆汤治疗胆总管结石的临床疗效。[方法]经B超、CT、逆行胰胆管造影(ERCP)明确诊断的胆总管结石,收集因无法行内镜下胆总管取石的30例患者,随机分为2组,2组均行内镜下胆总管支架置入术,A组给予常规西药治疗。B组在西药治疗的基础上,术后第2天给予化石利胆汤口服,在患者病情平稳后均停用西药治疗。分别在内支架基础上,B组继续给予化石利胆汤口服,2组治疗1个月后,行ERCP取石术,未成功者再于半年后行取石。[结果]B组腹痛腹胀及黄疸消退时间、术后排气排便时间及对比治疗1周后总胆红素、直接胆红素及白细胞计数下降情况,随访3个月、半年后再次取石成功率均显著优于A组,2组相比差异均具有统计学意义。[结论]内镜介入取石配合化石利胆汤治疗效果更好、更安全、可靠。 [ Objective ] To observe the curative effect of interventional endoscopy combined with Chinese herbs Huashi Lidan Decoction in the treatment of choledocholithiasis.[ methods ] Through examination with B ultrasound,CT,endoscopic retrograde cholangiopancreatography(ERCP),30patients of choledocholithiasis,who were not suitable to undergo ERCP lithotomy,were enrolled and randomly divided into 2 groups.After bile duct stent implantation to all subjects,patients in group A were treated with routine western medicine therapy.Pateitns in group B were treated additionally with Huashi Lidan Decoction aside from western medicine.Both groups were treated for 1month and then underwent ERCP lithotomy.Unsuccessful patients underwent ERCP lithotomy half a year later.[ Results ] Compared to group A,there were several advantages in group B,such as the duration of bellyache,abdominal distension,jaundice,postoperative exhaust defecation time,the decline of total bilirubin,direct bilirubin and white blood cell count after 1week of treatment,the successful rate at 3-month follow-up and also half-a-year follow-up.Results in group B were sgnificantly better than in group A,and the differences between the 2groups were statistically significant.[ Conclusion ] Endoscopic stone extraction combined with Chinese herbal decoction has good effect with reliable safety.
作者 季芳
出处 《中国中西医结合消化杂志》 CAS 2013年第7期346-348,共3页 Chinese Journal of Integrated Traditional and Western Medicine on Digestion
关键词 胆总管结石 化石利胆汤 胆管内支架 choledocholithiasis Huashi Lidan Decoction stenting of bile duct
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