摘要
目的探讨喉咽反流(LPR)与胃食管反流病(GERD)的关系及诊治方法。方法对43例反流性咽喉炎患者,收集患者症状、喉镜检查及部分患者胃食管镜检查、24 h食管pH监测结果,依据Belafsky等设立的反流症状指数(RSI)及反流征象分数(RSF)评估,均拟诊断LPR,给予质子泵抑制剂及必要口服胃动力药物治疗12周,比较患者治疗前后症状、喉镜及RSI和RSF评分判断治疗效果。结果治疗4周后总有效率为37.2%(16例),治疗6周后总有效率48.8%(21例),治疗8周后总有效率86.1%(37例),治疗12周后总有效率90.7%(39例)。结论针对可疑LPR患者行诊断性PPI治疗不失为一种简便易行且疗效确切的方法。
Objective To investigate the relationship between laryngopharyngeal reflux （LPR） and gastroesophageal reflux disease （GERD） and their treatment method. Methods A total of 43 patients with reflux laryngitis were studied on the basis of symptoms and the findings of laryngoscopy, gastroesophageal endoscopy in partial patients and 24-hour esophageal pH monitoring. They were all diagnosed as LPR according to reflux symptom index （RSI） and reflux syndrome as a fraction （RSF） assessment established by Belafsky. The treatment included proton pump inhibitor （PPI） and necessary oral gastric motility drugs for 12 weeks. Comparison was done between before and after the treatment. Results The total efficiency was 37.2% （ 16 cases） after 4 weeks＇ treatment, 48.8% （21 cases） after 6 weeks＇ treatment, 86.1% （37 cases） after 8 weeks＇ treatment and 90.7% （39 cases） after 12 weeks＇ treatment. Conclusion To the patients suspected of LPR, PPI therapy is a simple and effective method, and it is worthy of popularization and application.
出处
《临床军医杂志》
CAS
2013年第6期589-591,共3页
Clinical Journal of Medical Officers
关键词
胃食管反流
咽喉反流
质子泵抑制剂
gastroesophageal reflux disease
laryngopharyngeal reflux
proton pump inhibitor
