摘要
目的探讨免疫球蛋白E（IgE）及自细胞介素5（IL-5）在肺炎支原体感染合并支气管哮喘患儿诊断中的临床意义。方法选择住院治疗的肺炎支原体感染合并支气管哮喘患儿40例为观察组，另选择肺炎支原体感染未合并支气管哮喘患儿40例为对照组，所有患儿均在人院次日清晨抽取空腹静脉血检测IgE及IL一5水平。结果观察组患儿血清总IgE水平为（335．74±38．84）IU／ml，IL-5水平为（311.86±35．28）ng,／L，均显著高于对照组患儿（P〈0．05）。经二分类Logistic回归分析，血清IgE与IL-5水平均差异有统计学意义（P〈0．05）。结论肺炎支原体感染合并支气管哮喘患儿IgE与IL-5水平升高更加明显，且血清IgE与IL-5水平是肺炎支原体感染合并支气管哮喘患儿发病的重要危险因素。
Objective To explore the clinical value of IgE and IL-5 in diagnosis of mycoplasma pneumoniae children with bronchial asthma. Methods 40 mycoplasma pneumoniae infection children complicated with bronchial asthma were chosen as the observation group, the other 40 mycoplasma pneumoniae infection children without bronchi- al asthma were selected as the control group. All children were admitted to hospital, the next morning fasting blood was obtained to detect IgE and IL-5 levels. Results The serum total IgE level of observation group was （ 335.74±38.84 ）IU/ml ,the level of IL-5 was （311.86±35.28 ）ng/L ,which were significantly higher than control group （P 〈 0.05）. Binary Logistic regression analysis showed that, serum IgE level and IL-5 level had statistically significant difference （P 〈 0.05）. Conclusion Mycoplasma pneumoniae infection in children with bronchial asthma, the IgE and IL-5 levels increased more obviously, and the levels of serum IgE and IL-5 were important risk factors of onset of children with Mycoplasma pneumoniae infection combined bronchial asthma.
出处
《中国基层医药》
CAS
2013年第13期1975-1977,共3页
Chinese Journal of Primary Medicine and Pharmacy
