摘要
目的探讨去甲斑蝥素联合化疗治疗胃癌术后的临床疗效。方法将2005年7月至2008年7月淮南朝阳医院收治的82例Ⅱ～Ⅲ期胃癌术后患者,按照病案号用radna1软件随机分为单纯化疗组(41例)和联合化疗组(41例)。观察患者术后1、2、3年生存率与复发率。结果术后3年联合化疗组的生存率高于单纯化疗组(58.5%vs 36.5%),复发率低于单纯化疗组(26.8%vs 48.7%),差异均有统计学意义(χ2=3.96,4.20,P<0.05)。结论去甲斑蝥素联合化疗治疗胃癌术后患者,可提高生存率,降低肿瘤的复发。
Objective To investigate the clinical effect of chemotherapy combined with noreantharidin on the treatment of postoperative gastric cancer patients. Methods Eighty-two cases of postoperative gastric cancer（ stage I1- HI ） patients who received treatment in Chaoyang Hospital of Huainan from July in 2005 to July in 2008 were randomly （ using radnal software） divided into two groups, including 41 eases of chemother- apy group,41 cases of combined group. The 1-year, 2-year, 3-year survival rate and recurrence rate after operation were observed. Results 3-year survival 36.5% ） and the recurrence rate was lower（26.8% rate of the combination group was higher（58.5% vs vs 48.7% ）than the chemotherapy group with statistical- ly significant difference （ ~2 = 3.96,4.20, P 〈 0.05 ）. Conclusion Chemotherapy combined with canthari- din for treatment of postoperative gastric cancer can contribute to reduce the recurrence and improve the sur- vival rate.
出处
《医学综述》
2013年第11期2087-2088,共2页
Medical Recapitulate
关键词
去甲斑蝥素
化疗
胃癌术后
Norcantharidin
Chemotherapy
Postoperative gastric cancer
