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叶黄素治疗年龄相关性黄斑变性的临床研究 被引量:12

Clinical Trial of Lutein on Treatment of Age-related Macular Degeneration
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摘要 目的:观察叶黄素治疗年龄相关性黄斑变性的临床疗效。方法:采用随机、对照、双盲方法,观察83例患者服食叶黄素咀嚼片前后137只眼睛视力、眼底黄斑变化。结果:治疗组显效11眼,有效31眼,无效32眼,总有效率56.76%;对照组显效0眼,有效19眼,无效44眼,总有效率30.16%。2组比较有统计学意义(P<0.001)。结论:叶黄素对年龄相关性黄斑变性患者眼底表现及视力有一定改善作用。 Objective: To evaluate the clinical therapeutic effect of Lutein on the treatment of age-related macular degeneration (AMD). Methods: 137 eyes of 83 AMD patients were randomized in a controlled, double blind trial. The treatment group was treated with lutein chewable tablets and the control group were treated with placebo. After 3-month treatment, the changes of distant vision and puncta luteum in OCT were observed. Results:The total effective rate of the treatment group was 56.76%, significant better than 30.16% of the control group (P 〈 0. 001 ). Conclusion: Lutein showed therapeutic effect for age-related macular degeneration, such as improving visual activity, elimination of retina edema and atrophying.
出处 《世界中医药》 CAS 2013年第5期517-519,共3页 World Chinese Medicine
关键词 临床研究 年龄相关性黄斑变性 叶黄素 Clinical trial Age-related macular degeneration(AMD) Lutein
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