摘要
1例85岁女性患者为明确疾病诊断行下肢动脉及冠状动脉造影术,术中使用造影剂碘克沙醇150 ml。造影术前患者血尿素5.8 mmol/L,肌酐105μmol/L,钾4.2 mmol/L,钠134 mmol/L,氯97 mmol/L;造影术后第2天出现反酸、恶心、无尿,血尿素10.9 mmol/L,肌酐125μmol/L,尿蛋白(++);第3天仍旧少尿,血尿素13.0 mmol/L,肌酐170μmol/L,钾3.5 mmol/L,钠128 mmol/L,氯98 mmol/L。考虑为碘克沙醇所致急性肾损伤。给予利尿、血液滤过、纠正电解质紊乱等治疗,患者血肌酐水平逐渐下降,造影术后第16天患者好转出院。
An 85-year-old woman received lower limb arteries and coronary angiography in order to confirm the disease diagnosis. The contrast medium was iodixanol （150 ml ）. Laboratory examinations revealed the following levels ： blood urea 5.8 mmol/L, serum creatinine （SCr） 105 μmol/L, K ＋4.2 mmol/L, Na＋ 134 mmol/L, and C1- 97 mmol/L before the angiography. On day 2 of angiography, the patient developed acid regurgitation, nausea and anuria, laboratory examinations revealed the following levels： blood urea 10.9 mmol/L, SCr 125 μmol/L, urine protein （ ＋＋ ）. On day 3, the patient developed oliguria. Laboratory examinations revealed the following levels： blood urea 13.0 mmol/L, SCr 170μmol/L, K ＋3.5 mmol/L, Na＋ 128 mmol/L, C1- 98 mmol/L. The patient was considered as acute renal injury induced by iodixanol. After the treatments with diuresis, hemofihration, and correction of electrolyte imbalance, her serum creatinine level decreased gradually. Sixteenth days after angiography, the patient was improved and discharged.
出处
《药物不良反应杂志》
CSCD
2013年第2期93-94,共2页
Adverse Drug Reactions Journal
