摘要
目的:总结肥厚型梗阻性心肌病(HOCM)患者行左心室流出道疏通术的麻醉管理经验。方法:70例HOCM患者在全身麻醉体外循环下行左心室流出道疏通术,麻醉诱导和麻醉维持采用咪达唑仑、丙泊酚、异氟烷、芬太尼和哌库溴铵,术中持续监测ECG、HR、脉搏血氧饱和度(SPO2)、有创动脉血压(IBP)、中心静脉压(CVP)、心输出量(CO)、心脏排血指数(CI)、外周血管阻力(SVR)、肺血管阻力(PVR)及平均肺动脉压(MPAP)。术中部分患者使用艾司洛尔、去氧肾上腺素及地尔硫卓等维持血液动力学平稳。结果:术中血液动力学平稳,无严重心律失常发生,全组均顺利完成手术。结论:麻醉管理的关键在于①以适度的麻醉深度避免抑制心肌收缩力;②维持正常的心率和血压,酌情使用增强心肌收缩力的药物;③维持好前后负荷,避免使用血管扩张药;
Objective:To review the anesthetic management of left ventricular septal myectomy in patients with hypertrophic obstructive cardiomyopathy(HOCM).Methods: 70 consecutive patients with HOCM underwent left ventricular outflow septal myectomy under general anesthesia and cardiopulmonary bypass.Midazolam,propofol,fentanyl,isoflurance and pipecuronium were used to induce and maintain anesthesia.ECG,HR,SPO2,IBP,CVP,MAP,CO,CI,SVR,PVR,MPAP were monitored continuously.The medicinal usage of the Esmolol,Phenylephrine,Diltiazem made the hemodynamics stable in operation.Results: The hemodynamics was stable and there no serious ventricular arrhythmias occurred in operation.Conclusion: Anesthetic management should focus on the following strategies in patients with left ventricular septal myectomy: ①reduction of myocardial contractility by adequate deep anesthesia;②keeping sufficient preload and afterload,and avoiding the use of vasodilators;③maintaining adequate heart rate and blood pressure,and avoiding the use of positive inotropics.
出处
《心肺血管病杂志》
CAS
2013年第3期337-339,共3页
Journal of Cardiovascular and Pulmonary Diseases
基金
北京市卫生系统高层次人才项目-学科带头人(SF-2011-02-17)
关键词
肥厚型梗阻性心肌病
左心室流出道疏通术
麻醉管理
Hypertrophic obstructive cardiomyopathy
Left ventricular septal myectomy
Anesthetic management