摘要
目的探讨肿瘤患者与普通人群发生脑梗死的高危因素区别。方法选择2005年1月至2012年8月期间收住的恶性肿瘤伴脑梗死患者67例作为肿瘤组,随机抽取同期住院的符合纳入标准的普通脑梗死患者67例作为对照组,应用回归性对照研究对肿瘤患者发生脑梗死的高危因素进行分析。结果单因素分析显示肿瘤组患者伴有高血压、糖尿病、高脂血症等高危因素比率明显低于对照组(P<0.05或P<0.01),D-二聚体及纤维蛋白原水平异常率显著高于对照组(P<0.05或P<0.01),血小板水平异常率大致相同(P>0.05)。多因素回归分析显示高纤维蛋白原、高D-二聚体血症是肿瘤患者发生脑梗死的高危因素。结论肿瘤患者发生脑梗死的高危因素与普通人群不同,肿瘤相关高凝状态是肿瘤患者发生脑梗死的重要高危因素。
Aim To investigate the risk factors of cerebral infarction in cancer patients. Methods 67 cases of tumor patients with cerebral infarction were included as the tumor group who were treated in hospital from January 2005 to August 2012, 67 cases of general cerebral infarction were randomly selected at the same times as control group. The difference was analysed between tumor group and control group in hypertension, diabetes, hyperlipidemia, plasma fibrinogen and D-dimmer. Results Incidence of hypertension, diabetes and hyperlipidemia was significantly lower in tumor group （P〈0.05 or P 〈0.01） , D-dimmer and fibrinogen level was significantly higher than that of eontd group （P〈0.05 or P 〈0.01）. Multivariate regression analysis showed that plasma fibrinogen and D-dimmer were the risk factors of cerebral infarction in cancer patients. Conclusions Stroke risk factors are different between the cancer patients and gener- al people. Cancer-associated hypereoagulation is an important stroke risk factor in patients with cancer.
出处
《中国动脉硬化杂志》
CAS
CSCD
北大核心
2013年第5期457-459,共3页
Chinese Journal of Arteriosclerosis
关键词
肿瘤
脑梗死
高危因素
Cancer
Cerebral Infarction
Risk Factor
