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替罗非班在冠状动脉粥样硬化性心脏病治疗的中国专家共识 被引量:80

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摘要 血小板活化和聚集在动脉粥样硬化血栓形成的发病机制中起着关键作用,也是导致急性冠状动脉(冠脉)综合征(ACS)的直接原因。因此,抗血小板治疗贯穿冠心病治疗始终。目前,临床常用口服抗血小板药物均是在上游抑制血小板活化,而血小板膜蛋白(GP)IIb/IIIa抑制剂(GPI)作用在血小板聚集的最后环节,是最强的抗血小板药物。作为一种非肽类小分子GPI,替罗非班在ACS及经皮冠脉介入治疗(PCI)的患者中积累了大量临床研究证据,
出处 《中华内科杂志》 CAS CSCD 北大核心 2013年第5期434-439,共6页 Chinese Journal of Internal Medicine
基金 国家科技支撑计划(2011BA11B07)
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