摘要
主动脉瓣狭窄是临床常见的老年性瓣膜疾病,其发病率呈增高趋势。症状性重度主动脉瓣狭窄患者若不干预,其病死率明显增高。尽管该病首选治疗手段为手术治疗,但众多高龄、左心功能不全、体质差或合并多系统严重疾病的患者不能接受手术治疗。经导管主动脉瓣置换术为高危重度及手术禁忌的主动脉瓣狭窄患者带来了新的希望。现结合近年发表的相关文献对经导管主动脉瓣置换术在高危重度主动脉瓣狭窄患者中的应用进行综述。
Aortic stenosis is the clinical common valvular disease in aged people and the tendency of morbidity rates is increasing. Symptomatic severe aortic stenosis is associated with a high rate of death if left untreated. Although surgical aortic valve replacement is the first-line treatment, many patients are not surgical candidates, such as those with an advanced age or poor left ventricular function or other coexisting muhiple-systemic severe disorders. Transcatheter aortic valve replacement brings new hope for those with high-risk severe aortic stenosis and can not undergo surgery. Based on the available materials, we will review the update of the new therapy in high-risk severe aortic stenosis patients.
出处
《心血管病学进展》
CAS
2013年第2期186-189,共4页
Advances in Cardiovascular Diseases
