摘要
目的总结儿童和青少年颞叶癫癎手术后的长期疗效和生活质量。方法回顾性分析31例儿童和青少年颞叶癫癎病人的临床资料,行标准前颞叶切除术26例,扩大前颞叶切除术2例,前颞叶切除术+软化灶切除术2例,颞后顶下致癎灶切除术1例。评估术后癫癎发作改善情况及认知、生活质量等。结果术后随访5年以上,其中癫癎发作消失、达到EngelⅠ级26例,EngelⅡ级1例,EngelⅢ级2例,EngelⅣ级2例。术后病理示:海马组织硬化13例,皮质发育异常伴胶质增生9例,皮质发育异常伴海马组织硬化6例,神经元胶质肿瘤2例,继发性瘢痕脑回形成1例。术后并发症多数可恢复。结论儿童和青少年颞叶癫癎术后长期疗效良好,生活质量提高。
Objective To evaluate the long-term outcomes and quality of life after surgery in children and adolescents with temporal lobe epilepsy. Methods Clinical data of 31 children and adolescents with temporal lobe epilepsy were analyzed retrospectively. Surgery was performed in all the patients, including the standard anterior temporal lobectomy in 26, extended anterior temporal lobectomy in 2, standard anterior temporal lobectomy plus malacic focus resection in 2 and resection of posteriotemporal and subparietal epileptogenic focus in 1. The improvements of epileptic seizure, cognition and life quality were evaluated after surgery. Results During a follow-up period of more than 5 years, the patients achieved seizure-free and Engel class Ⅰ outcome in 26, Engel Ⅱ in 1, Engel Ⅲ in 2, Engel Ⅳ in 2. The postoperative pathological examination showed as follows： hippocampal sclerosis in 13 patients, cortical dysplasia and gliosis in 9, cortical dysplasia and hippocampal sclerosis in 6, gtioneuronal tumor in 2 and secondary scar gyrus formation in 1. Most postoperative complications were cured. Conclusion The long-term outcome is good and the quality-of-life could be improved after surgery for temporal lobe epilepsy in children and adolescents.
出处
《中国微侵袭神经外科杂志》
CAS
2013年第3期120-122,共3页
Chinese Journal of Minimally Invasive Neurosurgery
关键词
癫癎
颞叶
生活质量
随访研究
儿童
青少年
epilepsy, temporal lobe
quality-of-life
follow-up studies
child
adolescent
