摘要
目的 探讨1H磁共振波谱 (1HMRS)研究正常成人脑的价值。方法 选择 6 0例健康成人。1HMRS采用定点分辨波谱序列。结果 ①同年龄组一侧脑灰层的1HMRS波幅排列次序无变化 ;不同年龄组同一部位1HMRS波形与波幅不同。②NAA/CR及Glu n/CR随年龄的增长而上升 ,MI/CR随年龄的增长而下降 ,CHO/CR先下降后上升。同年龄组从前至后NAA/CR及MI/CR的比值下降。③ 5 0岁年龄段CHO/CR与年龄呈负相关 ;>5 0岁年龄段CHO/CR、MI/CR、Glu n/CR与年龄具有相关性。
Purpose To evaluate 1H Magnetic Resonance Spectroscopy ( HMRS) in the study of normal adult brain. Methods Sixty cases of healthy adults were selected,point resolved spectroscopy sequence was required for 1HMRS. Results ①No prominent difference of shape and peak arrangement was seen at the different ipsilateral site in the same age groups;while difference at the same site in the different age groups was present. ②The ratio of NAA/Cr and Glu\|n/CR was higher in senile age group;while that of MI/Cr was lower.The ratio of CHO/CR was in low\|to\|high order with the difference of age.The ratio of NAA/CR and MI/CR was gradually lower from anterior to posterior part of the brain.③Negative correlation of CHO/CR with age was present in groups aged lower than 50 years old;while correlation of CHO/CR\,MI/CR and Glu\|n/CR with age was present in groups aged greater than 50 years old. Conclusion 1HMRS plays an important role in the evaluation of biochemical changes in the normal adult brain. [
出处
《中国医学影像技术》
CSCD
北大核心
2000年第7期535-538,共4页
Chinese Journal of Medical Imaging Technology
基金
辽宁省自然科学基金
关键词
正常成人
脑
磁共振波谱
定量研究
Normal adult
Brain
Magnetic resonance spectroscopy
