摘要
目的评价参松养心胶囊对慢性心力衰竭患者心率变异性的影响。方法选择缺血性心肌病慢性心力衰竭患者40例,在常规抗心力衰竭治疗(利尿剂、血管紧张素转换酶抑制剂/血管紧张素受体抑制剂、β-受体阻滞剂、醛固酮拮抗剂及洋地黄制剂)的基础上加服参松养心胶囊1.6g,3次/d,连用8周。以超声心动图和24h动态心电图分别观察治疗前、治疗后8周患者的心脏功能和心率变异性的改变情况。结果参松养心胶囊治疗8周后左室射血分数、总体标准差(SDNN)、均值标准差(SDANN指数)较治疗前均显著增加,差异有统计学意义(P<0.05)。结论参松养心胶囊能够在一定程度上提高慢性心力衰竭患者心率变异性,明显改善心脏功能。
Objective To examine the effects of Shensongyangxin capsules on heart rate variability in optimally treated patients with chronic heart failure. Methods 40 patients with chronic heart failure being optimally treated （diuretic medicine, angiotensinogen converting enzyme inhibitors or angiotensin receptor blockers, β -blocker, aldosterone antagonists and digitalis） were added treatment of Shensongyangxin capsules 1.2g, 3 times/d. Echocardiography and 24 - hour heart rate variability analysis were analyses before and 8 weeks later. Results Shensongyangxin capsule in the treatment of 8 weeks after left ventricular ejection fraction, the overall standard deviation （SDNN）, mean standard deviation （SDANN index） were significantly increased compared with those before treatment, the difference was statistically significant （P 〈 0. 05）. Conclusion Shensongyangxin capsule can improve chronic heart failure patients with heart rate variability in a certain extent, improve cardiac function.
出处
《实用心脑肺血管病杂志》
2013年第3期55-56,共2页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词
参松养心胶囊
心率变异性
心力衰竭
Shensongyangxin capsules
Heart rate variability
Heart failure
