摘要
目的 研究乳腺分泌性癌的发病率、年龄和病理特点。方法 应用HE染色、淀粉酶消化后PAS及Alcianblue(AB)染色、透射电镜 (TEM)方法观察。结果 乳腺分泌性癌仅占同期全部活检乳腺癌的 0 .6 %。 4例平均年龄5 4 5岁。病理形态学的主要特点为癌细胞异型性较小 ,癌细胞能产生大量分泌物 ,对PAS及AB染色出现阳性反应。术后 12年随访 ,4例均无复发和转移。结论 乳腺分泌性癌为一种极少见的肿瘤 ,可发生于中老年女性 ,预后良好。根据其组织学特点 。
Objective To study the incidence, age, pathological features of secretory carcinoma of the breast. Methods Four cases of secretory carcinoma of the breast were collected from the archival material from 1973 to 1981. The specimens were stained with hematoxylin and eosin (HE), periodic acid schiff (PAS) with diastase pretreatment and alcian blue (AB) and observed with transmission electronic microscope. Results Four cases of secretory carcinoma of the breast accounted for only 0 6% (4/673) of the all breast carcinoma specimens in the same period .The average age was 54.5 (43～60). They were characterized by mild atypia of carcinoma cells and much secretory material in the cytoplasm positive for PAS and AB staining. The patients were followed up for 12 years after surgical resection without recurrence and metastasis. Conclusions Secretory carcinoma was a rare tumor and the prognosis of the patients was very good .It couldoccur in middle aged women. The pathological diagnosis could be made based on histological features of the tumor.
出处
《诊断病理学杂志》
CSCD
2000年第1期15-17,I008,共4页
Chinese Journal of Diagnostic Pathology
关键词
乳腺分泌性癌
中老年人
发病率
病理学
Mammary gland Secretory carcinoma of the breast Juvenile secretory carcinoma of the breast
