摘要
心肌炎是儿科心血管疾病的常见病，由心肌细胞水肿、浸润、凋亡和坏死所导致的心肌炎性病变是导致儿童心源性猝死的原因之一。心肌炎的表现多种多样，从无症状到致死性表现，这给心肌炎的临床诊断造成了困难。目前心肌炎的确诊手段主要是心内膜心肌穿刺活检，但由于心肌病变多为散在病灶，易造成采样误差，从而导致诊断准确性偏低。心脏磁共振成像不仅可以提供心脏解剖学和形态学的信息，还可以通过测量T1和T2弛豫时间及自旋密度来评价心肌组织特征（包括水肿、充血、纤维化）。现将心脏磁共振成像检测儿童心肌炎病理学特色和研究进展作一综述。
Myocarditis is a common pediatric cardiovascular disease. Myocardial inflammation caused by myocardial cell edema, infiltration, apoptosis and necrosis, is one of the reasons leading to sudden cardiac death in children. Clinical symptoms of myocarditis has a wide variety ,from asymptomatic to lethal performance, which caused difficulties to the clinical diagnostic for myocarditis. Endomyocardial biopsy is a widely accepted method for diagnosing myocarditis. The drawbacks of this method are reduced sensitivity given that myoearditis may be focal or regional, as well as lowered specificity due to interobserver variability. Cardiovascular magnetic resonance（CMR） can not only provide the cardiac anatomy and morphology information, but also can evaluate myocardial tissue characteristics including edema, hyperemia, fibrosis by measuring the T1 and T2 relaxation times and spin density. This article describes the pathology and research progress on CMR in detecting children myocarditis.
出处
《中华实用儿科临床杂志》
CAS
CSCD
北大核心
2013年第1期56-58,共3页
Chinese Journal of Applied Clinical Pediatrics
基金
北京市科技计划项目（Z111100067311030）
关键词
心脏磁共振成像
心肌炎
水肿
坏死
纤维化
Cardiovascular magnetic resonance
Myocarditis
Edema
Necrosis
Fibrosis
