摘要
目的系统观察阈下抑郁患者应用脑电生物反馈干预3周之后的转归，探索脑电生物反馈对阈下抑郁的干预效果。方法将符合纳入标准的60例患者按随机数字表法分为治疗组和对照组，每组30例。治疗组采用脑电生物反馈治疗仪进行干预治疗3周，每周治疗2次并评定1次；对照组不采用任何方法干预，观察3周，每周评定1次。连续观察3周和治疗后第6周随访，分别采用汉密尔顿抑郁量表（HAMD）、抑郁自评量表（SDS）和流行病学研究中心调查用抑郁量表（CES-D）对2组患者进行评分和分析，并以HAMD的减分率作为总体疗效标准。结果对阈下抑郁患者进行脑电生物反馈干预的治疗组疗效优于对照组，且差异有统计学意义（P〈0．01）。治疗3周后，治疗组痊愈率、显效率和有效率分别为23．33％、70．00％和6．67％，而相应的对照组分别为0．00％、10．00％和16．67％。治疗后，治疗组SDS和CES．D的评分较治疗前均明显下降（P〈0．05），且与对照组同时间点组间比较，差异均有统计学意义（P〈0．05）。结论脑电生物反馈能有效降低阈下抑郁患者的SDS、HAMD和CES-D评分；脑电生物反馈干预能有效改善患者的症状。
Objective To explore the effect of electroencephalographic biofeedback （EEGBF） on subclini- cal depression by observing patients＇ outcome after 3 weeks of EEGBF intervention. Methods Sixty depressed pa- tients were assigned to a treatment group and a control group using a random digits table, with 30 in each group. Pa- tients in the treatment group received EEGBF twice weekly for 3 weeks and were evaluated once a week; patients in control group were not treated but were also evaluated weekly. The patients were observed for 3 weeks, then followed up 6 weeks after the treatment had ended. Scores on the Hamilton depression scale （HAMD） , the self-rating depres- sion scale （SDS） and the Center for Epidemiology survey （CES-D） were analyzed. Reduced HAMD score was regar- ded as the standard for evaluating the effectiveness of EEGBF. Results The effect in the treated group was signifi- cantly better than in the control group. After 3 weeks of treatment, the rate of cure was 23% , excellence was rated 70% and effectiveness was 6.67%. The corresponding ratings for the control group were 0% , 10%o and 17% respec- tively. In treated group, SDS and CES-D scores were significantly lower than before treatment and significantly better than in the control group. Conclusion EEGBF can reduce patients＇ SDS, HAMD and CES-D scores and improve the signs of subclinical depression effectively.
出处
《中华物理医学与康复杂志》
CAS
CSCD
北大核心
2013年第2期140-143,共4页
Chinese Journal of Physical Medicine and Rehabilitation
基金
全军“十二五”面上项目（CWS11J284）
成都军区“十二五”重点项目（B12016）
