NT-proBNP对非ST抬高性心肌梗死患者近期预后的预测价值被引量：2

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摘要目的探讨NT-proBNP对急性非ST抬高性心肌梗死患者近期预后预测价值。方法入选的急性非ST抬高性心肌梗死患者依据其血浆NT-proBNP水平分为两组,即水平正常者为对照组,升高者为研究组。随访发病后1个月主要心血管事件。结果随访1个月对照组发生心血管事件心力衰竭4例、急性ST段心肌梗死1例,研究组有19例发生心血管事件心力衰竭12例、急性ST段心肌梗死5例、猝死2例,两组发生心血管事件有显著统计学差异(P<0.05)。结论临床NT-proBNP检测方便、快速,可以为NSTEMI患者危险分层提供依据,NT-proBNP是NSTEMI患者近期预后判断的重要因子。

作者胡萍

机构地区公安县人民医院

出处《中国医药指南》 2013年第2期162-163,共2页 Guide of China Medicine

关键词 NT-PROBNP 非ST段抬高性心肌梗死预后

分类号 R542.22 [医药卫生—心血管疾病]

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参考文献9

1Shapiro BP, Hen HH,Burnett JC JR,et al.Use of plasma brainnat- riuretic peptide concentration to aid in the diagnosis of heart failure [J].Mayo Clin Proe 2003,78(4):481-486.
2赵听,王萌.N端脑钠肽前体对心力衰竭诊断价值的研究[J].中老年学杂志,2007,27(13):1287-1289.
3孙延黄,杨向军.NT-proBNP对急性心肌梗死患者近期预后及心功能的预测价值[J].浙江临床医学,2012,14(2):144-146. 被引量：1
4柯元南,陈纪林.不稳定性心绞痛和非ST段抬高心肌梗死诊断与治疗指南[J].中华心血管病杂志,2007,35(4):295-304. 被引量：2165
5Palazzuoli A,Gallotta M,Quatrini I,et al.Natriuretic peptides(BNP and NT-proBNP): measurement and relevance in heart failure[J]. Vasc Health Risk Manag,2010,1 (6):411-418.
6Hunt SA,Abrabam WT.2009 focused update incorporated into the ACC/AHA 2005 guidelinefor the diagnosi and management of heart failure in adult:A report of the American College of Cardiology Foundation/American Heart Association task force on practice guideline developed in collaboration with the intern- ational society for Heart and Lung Trans-plantation. Association [J].Circulation,2009,119(14):391-479.
7丁连芹,李明,牟春平,赵晓辉.心肌梗塞患者血浆脑钠素N端前体肽与内皮素含量的相关性[J].心血管康复医学杂志,2006,15(6):540-541. 被引量：17
8morrow DA,De-lemos JA,sabatine MS,et al.Evaluation of B-type natriuretic peptide for risk assessment in unstable Angina/Non- ST-elevation myocardial infarction: B-type natriuretic peptide and prognosis in TACTICS-TIMI 18 FREE[J].JACC,2003,41 (8): 1264- 1272.
9Talwar S,Squire IB,Downie PF, et al.Plasma N terminal pro-brain natriuretic peptide and cardiotrophin 1 are raised in unstable angina [J].Heart,2000,84(4): 421-424.

二级参考文献41

1陈金明,陈思聪.内皮素在冠心病方面的研究进展[J].心血管病学进展,1995,16(5):284-287. 被引量：19
2李小鹰.阿司匹林在动脉硬化性心血管疾病中的临床应用:中国专家共识(2005)[J].中华心血管病杂志,2006,34(3):281-284. 被引量：194
3丁连芹,李明,牟春平,赵晓辉.心肌梗塞患者血浆脑钠素N端前体肽与内皮素含量的相关性[J].心血管康复医学杂志,2006,15(6):540-541. 被引量：17
4Omland T,Persson A,Leong Ng,et al.N-terminal pro-B-type natriuretic peptide and long time mortality in acute coronary syndromes.Circulation,2002,106(23):2913-2918.
5Hunt PJ,Richards AM,Nicholis MG,et al.Immunore-active amino-terminal pro-brain natriuretic peptide (NT-proBNP):a new marker of cardiac impairment.Clin Endocrinol,1997,47:287-296.
6Gegenhuber M.Time course of B-Type natriuretic peptide(BNP) and N-terminal ProBNP changes in patients with decompensated heart failure,Grin Chem,2004,50(2):454-456.
7Morrow DA,De-Lemos JA,Sabatine MS,et al.Evaluation of B-type natriuretic peptide for risk assessment in unstable angina/non-ST-elevation myocardial infarction:B-type natriuretic peptide and prognosis in TACTICS-TIMI 18.J Am Coll Cardiol,2003,41(8):1264-1272.
8Talwar S,Squire IB,Downie PF,et al.Plasma N terminal pro-brain natriuretic peptide and cardiotrophin I are raised in unstable angina.Heart,2000,84(4):421-424.
9Sabatine MS,Morrow DA,Delemos JA,et al.Acute changes in circulating natriuretic peptide levels in relation to myocardial ischemia.J Am Coll Cardiol,2004,44:1988-1995.
10Goetze JP,Gore A,Moller CH,et al.Acute myocardial hypoxia increases BNP gene expression.FASEB J,2004,18:1928-1930.