摘要
目的：研究填充物在乳腺癌根治术后调强放疗计划中的剂量并进行比较，并探讨乳腺癌根治术后调强放疗的理想方案。方法：选取15例乳腺癌根治术后病人进行计划设计，应用Pinnacle9．2计划系统，采用5-6个照射野制定两组计划，分别为加填充物（Bolus）和不加填充物计划，使用相同的剂量一体积约束条件，处方剂量均为200cGy／25day，比较这两个计划PTV的适形度和剂量均匀性，双全肺及患侧肺的V5，V20，V30等剂量学指标。结果：使用BOLUS的IMRT计划能获得较满意的剂量分布，两种方法相比，除了靶区剂量，其余危及器官的剂量受量差异均无统计学意义。肺受量改变不明确，P〉0．05。结论：加了BOLUS做调强计划，大大提高了计划的适形度和均匀性，对某些患者可以减少肺v20，v30等剂量。结论：建议临床对于对乳腺癌根治术后的患者，做IMRT计划时加入0．5cm的填充物，可以提高表面剂量和靶区适形度。
Objetcive： To study the dose of intensity modulated radiotherapy with bolus of post-operative patienta with breast cancer and study the appropriate treatment pianning.Methods： For 15 post-operative patients with breast cancer.with the same dose volume constrac,with 5-6 fields were design,5000 cGy dose was gave to PTV,and 200 cGy/Day,max dose ,min dose, mean dose in PTV,and dose volume of risk organs（OAR） were used for comparison of these plans.Results： The IMRT plan with bolus could produce a good dose distribution.conformity index （CI）and HI of target were improved as the addition of bolus.except for HI,the irradiated dose of other OARs had no diffrentce between these two plans.Conclusions： in order to improve the dose of i superficialand surface buildup dose,O.5 cm bolus is needed.
出处
《中国医学物理学杂志》
CSCD
2013年第1期3848-3850,共3页
Chinese Journal of Medical Physics
关键词
乳腺癌根治术
调强放疗
填充物
breast cancer with radical operation
intensity modulated radiotherapy
bolus
