摘要
目的观察干扰素联合康复新液治疗小儿手足口病的疗效。方法 2010年5月～2012年11月住院的110例手足口病患儿,随机分成治疗组58与对照组52例,两组性别及症状轻重差异无统计学意义(P>0.05)。治疗组予干扰素肌注及综合治疗,并联合康复新液口服及外用;对照组仅予干扰素抗病毒及综合治疗。结果治疗组退热时间为(2.25±0.40)d,手足口腔疱疹消退时间为(2.41±0.79)d,平均住院时间为(5.23±1.61)d,显效率为51.7%(30/58),总有效率为91.4%(53/58);对照组退热时间为(2.36±0.75)d,手足口腔疱疹消退时间为(3.21±0.63)d,平均住院时间为(6.41±1.58)d,显效率为30.8%(16/52),总有效率为76.9%(40/52);两组手足口腔疱疹消退时间、平均住院时间、显效率、总有效率差异有统计学意义(P<0.05)。结论干扰素联合康复新液治疗手足口病疗效显著。
Objective To investigate the efficiency of interferon combined with Kanfuxin liquid in treating children hand-foot and mouth disease （HFMD）. Methods One hundred and ten cases HFMD children from inpatient depart- ment during May 2010 to November 2012 were randomly enrolled into the treating group （58 cases）, and the control group （52 cases）. The sexual divition and the severity of＂ symptom of two groups had no significant difference （P 〉 0.05）. The treating group were administered interferon intramuscular injection and comprehensive therapy, and com- bined with Kangfuxin liquid, taken orally and external used. The control group were only given interferon and compre- hensive therapy. Results The treating group, cooling time was （2.25±0.40） d, hand-foot and mouth herpes regression time was （2.41±0.79） d, average length of stay was （5.23±1.61） d, obvious response rate was 51.7% （30/58）, overall re- sponse rate was 91.4% （53/58）. The control group, cooling time was （2.36±0.75） d, hand-foot and mouth herpes re gression time was （3.21±0.63） d, average length of stay was （6.41±1.58） d, obvious response rate was 30.8% （16/52）, overall response rate was 76.9% （40/52）. There were significant differences between two groups about hand-foot and mouth herpes regression time, average length of stay, obvious response rate and overall response rate （P 〈 0.05）. Con- clusion There is a good curative effect to use interferon combines with Kanfuxin liquid in treating HFMD .
出处
《中国当代医药》
2013年第4期85-86,共2页
China Modern Medicine
关键词
干扰素
康复新液
小儿
手足口病
Interferon
Kangfuxin liquid
Children
Hand-foot and mouth disease
